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- 01GJ5M9CZHCEZQRNMTJT5RFJR6 classification A1.
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 date "2023".
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 language "eng".
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 type journalArticle.
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 hasPart 01GMR3HPS16D96J5EW9PG5NZZK.pdf.
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 subject "Medicine and Health Sciences".
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 doi "10.1136/bjsports-2022-106066".
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 issn "0306-3674".
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 issn "1473-0480".
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 issue "16".
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 volume "57".
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 abstract "Despite the high prevalence of tendon pathology in athletes, the underlying pathogenesis is still poorly understood. Various aetiological theories have been presented and rejected in the past, but the tendon cell response model still holds true. This model describes how the tendon cell is the key regulator of the extracellular matrix and how pathology is induced by a failed adaptation to a disturbance of tissue homeostasis. Such failure has been attributed to various kinds of stressors (eg, mechanical, thermal and ischaemic), but crucial elements seem to be missing to fully understand the pathogenesis. Importantly, a disturbance of tissue pressure homeostasis has not yet been considered a possible factor, despite it being associated with numerous pathologies. Therefore, we conducted an extensive narrative literature review on the possible role of intratendinous pressure in the pathogenesis of tendon pathology. This review explores the current understanding of pressure dynamics and the role of tissue pressure in the pathogenesis of other disorders with structural similarities to tendons. By bridging these insights with known structural changes that occur in tendon pathology, a conceptual model was constituted. This model provides an overview of the possible mechanism of how an increase in intratendinous pressure might be involved in the development and progression of tendon pathology and contribute to tendon pain. In addition, some therapies that could reduce intratendinous pressure and accelerate tendon healing are proposed. Further experimental research is encouraged to investigate our hypotheses and to initiate debate on the relevance of intratendinous pressure in tendon pathology.".
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 author 013749FC-F0EE-11E1-A9DE-61C894A0A6B4.
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 author 041A196A-F0EE-11E1-A9DE-61C894A0A6B4.
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 author 0F0B3A7A-F0EE-11E1-A9DE-61C894A0A6B4.
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 author 227ACD32-F0EE-11E1-A9DE-61C894A0A6B4.
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 author F58C299C-F0ED-11E1-A9DE-61C894A0A6B4.
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 author urn:uuid:016ac97e-30c5-4cb9-8b61-ff60e2615b84.
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 dateCreated "2022-11-18T15:04:06Z".
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 dateModified "2024-12-12T20:24:22Z".
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 name "Exploring the role of intratendinous pressure in the pathogenesis of tendon pathology : a narrative review and conceptual framework".
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 pagination urn:uuid:d14c211f-88c1-47ee-8aa6-11bcc30754ca.
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 publisher urn:uuid:6db92573-c649-4223-ad43-2bde6e0c036a.
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 sameAs LU-01GJ5M9CZHCEZQRNMTJT5RFJR6.
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 sourceOrganization urn:uuid:47d3b75f-d856-4f13-8c7d-e67e7284ed3d.
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 sourceOrganization urn:uuid:baacad25-0c9d-4a54-9cb0-93b38f271da3.
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 sourceOrganization urn:uuid:c17027e6-4b1f-4702-aae7-e94f75c30bfb.
- 01GJ5M9CZHCEZQRNMTJT5RFJR6 type A1.