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- 01GJQ35C2FR1AGZ51TSDM55TB4 classification A1.
- 01GJQ35C2FR1AGZ51TSDM55TB4 date "2023".
- 01GJQ35C2FR1AGZ51TSDM55TB4 language "eng".
- 01GJQ35C2FR1AGZ51TSDM55TB4 type journalArticle.
- 01GJQ35C2FR1AGZ51TSDM55TB4 hasPart 01GJQC58HDTJ5E5H75WN01XTYH.pdf.
- 01GJQ35C2FR1AGZ51TSDM55TB4 hasPart 01GM3E1RHNV2QA17ZGGV6NZDT4.pdf.
- 01GJQ35C2FR1AGZ51TSDM55TB4 subject "Medicine and Health Sciences".
- 01GJQ35C2FR1AGZ51TSDM55TB4 doi "10.1146/annurev-pathol-042220-015902".
- 01GJQ35C2FR1AGZ51TSDM55TB4 issn "1553-4006".
- 01GJQ35C2FR1AGZ51TSDM55TB4 issn "1553-4014".
- 01GJQ35C2FR1AGZ51TSDM55TB4 issue "1".
- 01GJQ35C2FR1AGZ51TSDM55TB4 volume "18".
- 01GJQ35C2FR1AGZ51TSDM55TB4 abstract "Despite the advent of sophisticated and efficient new biologics to treat inflammation in asthma, the disease persists. Even following treatment, many patients still experience the well-known symptoms of wheezing, shortness of breath, and coughing. What are we missing? Here we examine the evidence that mucus plugs contribute to a substantial portion of disease, not only by physically obstructing the airways but also by perpetuating inflammation. In this way, mucus plugs may act as an immunogenic stimulus even in the absence of allergen or with the use of current therapeutics. The alterations of several parameters of mucus biology, driven by type 2 inflammation, result in sticky and tenacious sputum, which represents a potent threat, first due to the difficulties in expectoration and second by acting as a platform for viral, bacterial, or fungal colonization that allows exacerbations. Therefore, in this way, mucus plugs are an overlooked but critical feature of asthmatic airway disease.".
- 01GJQ35C2FR1AGZ51TSDM55TB4 author E2A24524-AE32-11E8-9E72-4A0A5707D3EF.
- 01GJQ35C2FR1AGZ51TSDM55TB4 author F946B58E-F0ED-11E1-A9DE-61C894A0A6B4.
- 01GJQ35C2FR1AGZ51TSDM55TB4 dateCreated "2022-11-25T09:51:08Z".
- 01GJQ35C2FR1AGZ51TSDM55TB4 dateModified "2024-12-12T10:21:14Z".
- 01GJQ35C2FR1AGZ51TSDM55TB4 name "The pathology of asthma : what is obstructing our view?".
- 01GJQ35C2FR1AGZ51TSDM55TB4 pagination urn:uuid:81f2bef0-8fc2-4902-81fc-b58ad3dc72b5.
- 01GJQ35C2FR1AGZ51TSDM55TB4 sameAs LU-01GJQ35C2FR1AGZ51TSDM55TB4.
- 01GJQ35C2FR1AGZ51TSDM55TB4 sourceOrganization urn:uuid:270a4950-b097-4306-a134-fc46b80b92e0.
- 01GJQ35C2FR1AGZ51TSDM55TB4 sourceOrganization urn:uuid:922c2ee5-da00-4006-be1d-4804f41b9716.
- 01GJQ35C2FR1AGZ51TSDM55TB4 type A1.