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- 01GK970Q4E357N6BDSSB97HJFX classification A1.
- 01GK970Q4E357N6BDSSB97HJFX date "2022".
- 01GK970Q4E357N6BDSSB97HJFX language "eng".
- 01GK970Q4E357N6BDSSB97HJFX type journalArticle.
- 01GK970Q4E357N6BDSSB97HJFX hasPart 01GK971G6YQB8ZSYFQH8VMTM5W.pdf.
- 01GK970Q4E357N6BDSSB97HJFX subject "Medicine and Health Sciences".
- 01GK970Q4E357N6BDSSB97HJFX doi "10.1007/s12016-021-08901-1".
- 01GK970Q4E357N6BDSSB97HJFX issn "1080-0549".
- 01GK970Q4E357N6BDSSB97HJFX issn "1559-0267".
- 01GK970Q4E357N6BDSSB97HJFX issue "1".
- 01GK970Q4E357N6BDSSB97HJFX volume "62".
- 01GK970Q4E357N6BDSSB97HJFX abstract "Immunoglobulin E (IgE) is a well-known key factor in allergic airway disease; however, its central role in non-allergic airway inflammation is often underestimated. In some airway diseases, IgE is produced as a result of allergic sensitization. However, in others, IgE production occurs despite the lack of a specific allergen. Although multiple pathways contribute to the production of IgE in airway disease, it is its activity in mediating the inflammatory response that is associated with disease. Therefore, an understanding of IgE as the unifying component of upper and lower airway diseases has important implications for both diagnosis and treatment. Understanding the role of IgE in each upper and lower airway disease highlights its potential utility as a diagnostic marker and therapeutic target. Further classification of these diseases by whether they are IgE mediated or non-IgE mediated, rather than by the existence of an underlying allergic component, accounts for both systemic and localized IgE activity. Improvements in diagnostic methodologies and standardization of clinical practices with this classification in mind can help identify patients with IgE-mediated diseases. In doing so, this group of patients can receive optimal care through targeted anti-IgE therapeutics, which have already demonstrated efficacy across numerous IgE-mediated upper and lower airway diseases.".
- 01GK970Q4E357N6BDSSB97HJFX author F58DCC8E-F0ED-11E1-A9DE-61C894A0A6B4.
- 01GK970Q4E357N6BDSSB97HJFX author urn:uuid:1d4c7a07-8e15-4ca6-8106-af73bbf5eec6.
- 01GK970Q4E357N6BDSSB97HJFX author urn:uuid:9e8a7832-b69e-407e-b140-accdc4fc4963.
- 01GK970Q4E357N6BDSSB97HJFX author urn:uuid:de943c30-1536-46ef-979f-946d72f06688.
- 01GK970Q4E357N6BDSSB97HJFX dateCreated "2022-12-02T10:44:49Z".
- 01GK970Q4E357N6BDSSB97HJFX dateModified "2024-11-27T13:28:20Z".
- 01GK970Q4E357N6BDSSB97HJFX name "The role of IgE in upper and lower airway disease : more than just allergy!".
- 01GK970Q4E357N6BDSSB97HJFX pagination urn:uuid:f14dae6d-d488-4b9a-9edc-b6a53b92745d.
- 01GK970Q4E357N6BDSSB97HJFX publisher urn:uuid:2b8318f9-2fbf-4a5b-b27d-2d8ea88fd8a3.
- 01GK970Q4E357N6BDSSB97HJFX sameAs LU-01GK970Q4E357N6BDSSB97HJFX.
- 01GK970Q4E357N6BDSSB97HJFX sourceOrganization urn:uuid:03b9f97f-c422-4aa4-8d60-5904c9147321.
- 01GK970Q4E357N6BDSSB97HJFX sourceOrganization urn:uuid:a269bd10-9612-478f-aa4b-2678462b98d6.
- 01GK970Q4E357N6BDSSB97HJFX type A1.