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- 01GMMXC41FW48SCDYEHCVBTP4T classification A1.
- 01GMMXC41FW48SCDYEHCVBTP4T date "1999".
- 01GMMXC41FW48SCDYEHCVBTP4T language "eng".
- 01GMMXC41FW48SCDYEHCVBTP4T type journalArticle.
- 01GMMXC41FW48SCDYEHCVBTP4T subject "Chemistry".
- 01GMMXC41FW48SCDYEHCVBTP4T doi "10.1021/jo9823442".
- 01GMMXC41FW48SCDYEHCVBTP4T issn "0022-3263".
- 01GMMXC41FW48SCDYEHCVBTP4T issue "8".
- 01GMMXC41FW48SCDYEHCVBTP4T volume "64".
- 01GMMXC41FW48SCDYEHCVBTP4T abstract "The synthesis of the fluorous amine scavenger [(C6F13CH2CH2)(3)SiCH2CH2CH2](2)NH and its successful application in the automated solution phase parallel synthesis of a urea library are described. Ureas were made by robotic synthesis from organic amines and excess isocyanates. The amine scavenger reacts with excess isocyanate, and the fluorous tag serves to solubilize the resulting adduct in the fluorous phase so it can be removed by fluorous-organic extraction. Organic urea products are isolated in high yields and purities after liquid-liquid extraction. Preliminary biological evaluation shows that several of the ureas have ion channel modulation abilities. In contrast to polymer and ionic quenching methods, the fluorous quench works whether the product is soluble or insoluble in the reaction medium, and ionizable functional groups are tolerated in the products.".
- 01GMMXC41FW48SCDYEHCVBTP4T author 1CD7F116-2AE5-11E3-A4E0-796A10BDE39D.
- 01GMMXC41FW48SCDYEHCVBTP4T author urn:uuid:5ba6e340-9c2f-4cf4-9a7a-5511fb1d5d67.
- 01GMMXC41FW48SCDYEHCVBTP4T author urn:uuid:e46a5896-52b9-49af-b9a3-d4f5c493a2dc.
- 01GMMXC41FW48SCDYEHCVBTP4T dateCreated "2022-12-19T10:02:52Z".
- 01GMMXC41FW48SCDYEHCVBTP4T dateModified "2024-07-09T07:41:52Z".
- 01GMMXC41FW48SCDYEHCVBTP4T name "Organic-fluorous phase switches : a fluorous amine scavenger for purification in solution phase parallel synthesis".
- 01GMMXC41FW48SCDYEHCVBTP4T pagination urn:uuid:320c680c-a2e5-4ef7-afc3-fd670dee1bab.
- 01GMMXC41FW48SCDYEHCVBTP4T sameAs LU-01GMMXC41FW48SCDYEHCVBTP4T.
- 01GMMXC41FW48SCDYEHCVBTP4T sourceOrganization urn:uuid:c2be12f9-06fc-4997-a44d-2f0dbe8762e0.
- 01GMMXC41FW48SCDYEHCVBTP4T type A1.