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- 01HET2FVPTW6M14NMG2QFWZQNQ classification C3.
- 01HET2FVPTW6M14NMG2QFWZQNQ date "2023".
- 01HET2FVPTW6M14NMG2QFWZQNQ language "eng".
- 01HET2FVPTW6M14NMG2QFWZQNQ type conference.
- 01HET2FVPTW6M14NMG2QFWZQNQ hasPart 01HET3056E4VCD1WE765SDB9AZ.pdf.
- 01HET2FVPTW6M14NMG2QFWZQNQ subject "Biology and Life Sciences".
- 01HET2FVPTW6M14NMG2QFWZQNQ subject "Medicine and Health Sciences".
- 01HET2FVPTW6M14NMG2QFWZQNQ subject "Technology and Engineering".
- 01HET2FVPTW6M14NMG2QFWZQNQ presentedAt urn:uuid:4017dbf3-6a27-40a8-b88b-b7fa5674cc84.
- 01HET2FVPTW6M14NMG2QFWZQNQ abstract "Background: Arterial stiffness can be assessed via carotid-femoral pulse-wave velocity (cfPWV), a biomarker that can be reliably measured via, amongst others, laser-doppler vibrometry (LDV) [1]. The aim of this study is to benchmark LDV measurements, acquired in an ongoing study, against reference techniques as the Sphygmocor system, thereby validating this technology. Methods: 22 Patients (ages 24 – 78) had their cfPWV measured during a clinical feasibility study using the CARDIS (H2020 grant ID: 644798) LDV device. A new software was installed providing real-time filters and signal quality feedback [2]. Each patient had 3 measurements taken. All measurements were inspected and graded visually with scores ranging from 1 (very bad) to 5 (perfect). Heartbeats were visually identified in the LDV signals to get as reliable pulse-transit times (PTT) as possible. Resulting PTT’s were compared to Sphygmocor values also measured for every patient. Results: Good quality signals (scores 4-5) were obtained In 14/22 subjects. The mean difference in transit times between LDV and Sphygmocor was -1.14 (± 6.83) ms, with a correlation coefficient of 0.91 (P<0.05) (see Figure). Conclusions: The data confirm that LDV potentially allows measuring cfPWV with an accuracy comparable to Sphygmocor, provided an adequate signal quality can be achieved. We are further improving real-time signal quality feedback and, importantly, working on a prototype that will no longer require the use of retroreflective patches in the neck and groin (INSIDE project, H2020 grant ID: 871547 ). Reference list: [1] Y. Li, L. Marais, H. Khettabet, al. Silicon photonics-based laser Doppler vibrometer array for carotid-femoral pulse wave velocity (PWV) measurement. Biomedical Optics Express. 11(7), p.3913-3926. Published: June 22, 2020. doi:10.1364/BOE.394921 [2] Seoni S, Beeckman S, Li Y, et al. Template Matching and Matrix Profile for Signal Quality Assessment of Carotid and Femoral Laser Doppler Vibrometer Signals. Front Physiol. 2022;12:775052. Published 2022 Jan 11. doi:10.3389/fphys.2021.775052".
- 01HET2FVPTW6M14NMG2QFWZQNQ author 4118DE52-A6F4-11E7-8878-09B7AD28A064.
- 01HET2FVPTW6M14NMG2QFWZQNQ author 463F6876-3936-11E4-975D-9EF2B4D1D7B1.
- 01HET2FVPTW6M14NMG2QFWZQNQ author F4A2EB1A-F0ED-11E1-A9DE-61C894A0A6B4.
- 01HET2FVPTW6M14NMG2QFWZQNQ author FB8B0476-F0ED-11E1-A9DE-61C894A0A6B4.
- 01HET2FVPTW6M14NMG2QFWZQNQ author urn:uuid:02bdc6a3-b860-4fcc-a5a3-91fb110403fc.
- 01HET2FVPTW6M14NMG2QFWZQNQ author urn:uuid:18a83206-5df7-43ee-bd86-c593fa1148d9.
- 01HET2FVPTW6M14NMG2QFWZQNQ author urn:uuid:4ad05b40-17ef-4293-b7b1-8e745e11fef4.
- 01HET2FVPTW6M14NMG2QFWZQNQ author urn:uuid:b0e073ea-c6b8-4c65-bd3a-784bf98475d9.
- 01HET2FVPTW6M14NMG2QFWZQNQ dateCreated "2023-11-09T12:56:37Z".
- 01HET2FVPTW6M14NMG2QFWZQNQ dateModified "2024-10-29T18:33:29Z".
- 01HET2FVPTW6M14NMG2QFWZQNQ name "Measuring carotid-femoral pulse-wave velocity with real-time laser-doppler vibrometry".
- 01HET2FVPTW6M14NMG2QFWZQNQ publisher urn:uuid:4b9dc2fa-ae1d-4953-8cf9-37a43f53bf04.
- 01HET2FVPTW6M14NMG2QFWZQNQ sameAs LU-01HET2FVPTW6M14NMG2QFWZQNQ.
- 01HET2FVPTW6M14NMG2QFWZQNQ sourceOrganization urn:uuid:15006884-68a8-4939-a4a6-69c15c5b2122.
- 01HET2FVPTW6M14NMG2QFWZQNQ sourceOrganization urn:uuid:55b99a65-3f15-430e-93ff-7c6c9da711ce.
- 01HET2FVPTW6M14NMG2QFWZQNQ sourceOrganization urn:uuid:f5fdfd58-5d09-4523-91b5-6e83b607848f.
- 01HET2FVPTW6M14NMG2QFWZQNQ type C3.