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- 01HNWCVJKXQS89TZGQKW85BQVF classification C3.
- 01HNWCVJKXQS89TZGQKW85BQVF date "2023".
- 01HNWCVJKXQS89TZGQKW85BQVF language "eng".
- 01HNWCVJKXQS89TZGQKW85BQVF type conference.
- 01HNWCVJKXQS89TZGQKW85BQVF hasPart 01HNWCW7DZKXZZG1CDA66JPY4T.pdf.
- 01HNWCVJKXQS89TZGQKW85BQVF subject "Veterinary Sciences".
- 01HNWCVJKXQS89TZGQKW85BQVF doi "10.1111/jvp.13329".
- 01HNWCVJKXQS89TZGQKW85BQVF issn "0140-7783".
- 01HNWCVJKXQS89TZGQKW85BQVF issn "1365-2885".
- 01HNWCVJKXQS89TZGQKW85BQVF issue "Supplement 1".
- 01HNWCVJKXQS89TZGQKW85BQVF presentedAt urn:uuid:b88520e5-f3a3-4db7-8111-ed11f3622e6a.
- 01HNWCVJKXQS89TZGQKW85BQVF volume "46".
- 01HNWCVJKXQS89TZGQKW85BQVF abstract "Poultry production is expected to increase in Kenya by 375% from 35 million birds in 2012 to 166 million birds by 2050. This intensifi cation is posited to lead to increased antibiotic use which is a major driver of antimicrobial resistance (AMR). Antibiotics are commonly used in Kenya to treat infections, without prior diagnostic tests, for prophylaxis and as growth promoters. AMR studies tend to focus on bacterial isolation and the determination of specific AMR phenotypes and genotypes. This narrow approach only charac terizes a very limited proportion of the circulating resistome as bacteria exist as communities, where interspecies interactions play a role in the dissemination of AMR genes (ARGs). This study aims to apply a culture- independent method to characterize the diversity and relative abundance of the resistome in small- holder broiler farms (200– 2000 birds) and investigate any associations between ARG abundance and diversity and farming/production practices. We hypothesize that resistome is not affected by farm demographic and production practices. To test this hypothesis, genomic DNA extracted from composite fecal samples collected from 129 broiler farms in three peri- urban counties will be ana lyzed using the SmartChip™ Real- Time PCR system by Resistomap Oy (Helsinki, Finland). Ecological models and ordination methods will be implored to predict and analyze variation in ARG diversity and composition by demographic and production parameters. This study will provide novel information on the breath of ARGs cir culating in small holder broiler production systems and identify potential ARG farm profiles that can be used to better inform the design of interventions to decrease the development and spread of AMR from broiler farms.".
- 01HNWCVJKXQS89TZGQKW85BQVF author 046C8218-F0EE-11E1-A9DE-61C894A0A6B4.
- 01HNWCVJKXQS89TZGQKW85BQVF author b6ed6721-45c2-11ed-b836-d90d13e685c5.
- 01HNWCVJKXQS89TZGQKW85BQVF author urn:uuid:6b3f9a10-df01-43a4-b347-c746f16df1a9.
- 01HNWCVJKXQS89TZGQKW85BQVF author urn:uuid:b6fbc52f-1b32-451b-a2d6-601ef6a03bf6.
- 01HNWCVJKXQS89TZGQKW85BQVF author urn:uuid:d045afc6-6dce-4252-a22b-89dad88b42eb.
- 01HNWCVJKXQS89TZGQKW85BQVF author urn:uuid:e258d14b-d4a9-4760-a867-4c0adceafb88.
- 01HNWCVJKXQS89TZGQKW85BQVF dateCreated "2024-02-05T10:26:09Z".
- 01HNWCVJKXQS89TZGQKW85BQVF dateModified "2024-12-12T20:49:03Z".
- 01HNWCVJKXQS89TZGQKW85BQVF name "Abundance and diversity of the fecal resistome in small-holder broiler systems in Kenya".
- 01HNWCVJKXQS89TZGQKW85BQVF pagination urn:uuid:0a76524f-65ca-474b-a922-95f843a6c9a9.
- 01HNWCVJKXQS89TZGQKW85BQVF sameAs LU-01HNWCVJKXQS89TZGQKW85BQVF.
- 01HNWCVJKXQS89TZGQKW85BQVF sourceOrganization urn:uuid:739f8248-5591-4d14-8d9c-b17d04f30e38.
- 01HNWCVJKXQS89TZGQKW85BQVF type C3.