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- 01J9XRPDJ01WCGNHHP10GE6ZH7 classification A1.
- 01J9XRPDJ01WCGNHHP10GE6ZH7 date "2024".
- 01J9XRPDJ01WCGNHHP10GE6ZH7 language "eng".
- 01J9XRPDJ01WCGNHHP10GE6ZH7 type journalArticle.
- 01J9XRPDJ01WCGNHHP10GE6ZH7 hasPart 01J9XS0JJ0PMHHY53AWN8C1NC1.docx.
- 01J9XRPDJ01WCGNHHP10GE6ZH7 subject "Chemistry".
- 01J9XRPDJ01WCGNHHP10GE6ZH7 subject "Medicine and Health Sciences".
- 01J9XRPDJ01WCGNHHP10GE6ZH7 doi "10.1002/macp.202400277".
- 01J9XRPDJ01WCGNHHP10GE6ZH7 issn "1022-1352".
- 01J9XRPDJ01WCGNHHP10GE6ZH7 issn "1521-3935".
- 01J9XRPDJ01WCGNHHP10GE6ZH7 abstract "Digital light processing (DLP) is emerging as a powerful tool for fabricating tissue engineering (TE) scaffolds, particularly for vascular TE and the development of representative in vitro vascular wall models. For the latter, biomaterials should mimick the biological and mechanical properties of native blood vessels. To fabricate tubular constructs, the DLP‐printing process is optimized by exploiting acrylate‐endcapped urethane‐based (AUP) polymers as the presence of the acrylate end groups render them suitable for DLP printing and desirable mechanical properties arise from the urethane segments. Four AUP variants are synthesized, exploring polyethylene glycol (PEG) and polypropylene glycol (PPG) backbones with varying acrylate functionalities (di‐acrylate versus hexa‐acrylate), namely UPEG2, UPEG6, UPPG2, and UPPG6. Tubular constructs with precise dimensions and morphology are fabricated. PPG‐based AUP polymers exhibit superior computer‐aided design/manufacturing (CAD/CAM) mimicry compared to PEG‐based derivatives. Construct characterization reveals tunable mechanical properties, with elastic moduli ranging from 45 to 259 kPa, reaching values of the human blood vessels. In particular, UPPG6 shows a two‐fold higher elastic modulus compared to UPPG2. All materials show excellent biocompatibility. Additionally, surface modification with gelatin‐methacryloyl (GELMA) significantly enhances the cytocompatibility of UPPG2 scaffolds. This study demonstrates the feasibility of fabricating tubular constructs with tunable properties using DLP and AUP polymers.".
- 01J9XRPDJ01WCGNHHP10GE6ZH7 author 32481fb2-f340-11ec-8c23-b6a6773ba13e.
- 01J9XRPDJ01WCGNHHP10GE6ZH7 author 3C783F08-F0EE-11E1-A9DE-61C894A0A6B4.
- 01J9XRPDJ01WCGNHHP10GE6ZH7 author 99ED24CC-1E7E-11E4-B0FC-3B54B5D1D7B1.
- 01J9XRPDJ01WCGNHHP10GE6ZH7 author A585852E-82CE-11E7-BA37-6BFDAD28A064.
- 01J9XRPDJ01WCGNHHP10GE6ZH7 author EAE7D06C-5E7C-11E6-BCAC-C275B5D1D7B1.
- 01J9XRPDJ01WCGNHHP10GE6ZH7 author F6EFF23C-F0ED-11E1-A9DE-61C894A0A6B4.
- 01J9XRPDJ01WCGNHHP10GE6ZH7 author F7AF8B88-F0ED-11E1-A9DE-61C894A0A6B4.
- 01J9XRPDJ01WCGNHHP10GE6ZH7 author urn:uuid:3db3470b-1752-411b-aa84-78f2b94414d9.
- 01J9XRPDJ01WCGNHHP10GE6ZH7 author urn:uuid:66977256-c4b8-4a44-b446-ee283e2a72a1.
- 01J9XRPDJ01WCGNHHP10GE6ZH7 dateCreated "2024-10-11T12:26:13Z".
- 01J9XRPDJ01WCGNHHP10GE6ZH7 dateModified "2024-12-12T21:15:08Z".
- 01J9XRPDJ01WCGNHHP10GE6ZH7 name "Toward in vitro vascular wall models : digital light processing of acrylate‐edcapped urethane‐based polymers into tubular constructs".
- 01J9XRPDJ01WCGNHHP10GE6ZH7 sameAs LU-01J9XRPDJ01WCGNHHP10GE6ZH7.
- 01J9XRPDJ01WCGNHHP10GE6ZH7 sourceOrganization urn:uuid:9c63936b-9ee7-444a-99c8-a9c863a5ecd6.
- 01J9XRPDJ01WCGNHHP10GE6ZH7 sourceOrganization urn:uuid:b413f63a-dca2-41ff-a064-d9d46b376ac9.
- 01J9XRPDJ01WCGNHHP10GE6ZH7 type A1.