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- 01JE0VTPCZAB9N12DA72WNKA79 classification A1.
- 01JE0VTPCZAB9N12DA72WNKA79 date "2025".
- 01JE0VTPCZAB9N12DA72WNKA79 language "eng".
- 01JE0VTPCZAB9N12DA72WNKA79 type journalArticle.
- 01JE0VTPCZAB9N12DA72WNKA79 hasPart 01JE3ZKNX5PERFFNE5FTSDGQNV.pdf.
- 01JE0VTPCZAB9N12DA72WNKA79 subject "Agriculture and Food Sciences".
- 01JE0VTPCZAB9N12DA72WNKA79 doi "10.1016/j.ijfoodmicro.2024.110940".
- 01JE0VTPCZAB9N12DA72WNKA79 issn "0168-1605".
- 01JE0VTPCZAB9N12DA72WNKA79 issn "1879-3460".
- 01JE0VTPCZAB9N12DA72WNKA79 volume "427".
- 01JE0VTPCZAB9N12DA72WNKA79 abstract "Whole-Genome Sequencing has the potential to be an effective method for surveillance of foodborne diseases. This study aims to determine the genetic relatedness and prevalence of virulence-associated genes and antimicrobial resistance determinants in 135 Campylobacter jejuni, seven Campylobacter coli and three Campylobacter lari isolates from the poultry supply chain and a hospital in Spain. The isolates showed a wide genetic diversity between and within species with Clonal Complex 21 the most frequent lineage found. Among species, C. jejuni showed the highest prevalence of virulence genes (287/333) in which a high occurring variability was observed in the capsule biosynthesis and transport, O-linked flagellar glycosylation and lipooligosaccharide biosynthesis loci, with a great impact of phase-variation that led to 72 different virulence gene patterns among all isolates. High prevalence (> 90 %) of blaOXA-type β-lactamase genes and mutations in DNA gyrase gene associated with fluoroquinolones resistance were observed, and at a frequency similar to the tet(O) gene in C. jejuni (93 %) and C. coli (86 %), both of which also harboured resistance determinants to aminoglycosides with a higher occurrence rate in C. coli (43 %), that was the only species in which mutations in the 23S ribosomal subunit conferring resistance to erythromycin were identified (43 %). The present study constitutes the largest genomic survey of Campylobacter isolates in Spain providing insight into the prevalence and diversity of the pathogen along the poultry supply chain in the country.".
- 01JE0VTPCZAB9N12DA72WNKA79 author dc876a06-1b7f-11ee-a0a6-a5738e2942d5.
- 01JE0VTPCZAB9N12DA72WNKA79 author urn:uuid:1e02cb6a-4fc1-44a2-bc50-0632b71ebd91.
- 01JE0VTPCZAB9N12DA72WNKA79 author urn:uuid:ead3b6c2-e0ea-4a0e-af4e-f1212704be99.
- 01JE0VTPCZAB9N12DA72WNKA79 dateCreated "2024-12-01T10:21:30Z".
- 01JE0VTPCZAB9N12DA72WNKA79 dateModified "2024-12-12T21:14:15Z".
- 01JE0VTPCZAB9N12DA72WNKA79 name "Whole-genome comparative analysis of the genetic, virulence and antimicrobial resistance diversity of Campylobacter spp. from Spain".
- 01JE0VTPCZAB9N12DA72WNKA79 pagination urn:uuid:7f7f98ac-8ab1-4a26-9c4f-33374b043d9a.
- 01JE0VTPCZAB9N12DA72WNKA79 sameAs LU-01JE0VTPCZAB9N12DA72WNKA79.
- 01JE0VTPCZAB9N12DA72WNKA79 sourceOrganization urn:uuid:50582d68-8db6-47ef-b070-2c1960c120ca.
- 01JE0VTPCZAB9N12DA72WNKA79 type A1.