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- 01JH3CD1FMPT60HSDNZFP9XG65 classification A1.
- 01JH3CD1FMPT60HSDNZFP9XG65 date "2025".
- 01JH3CD1FMPT60HSDNZFP9XG65 language "eng".
- 01JH3CD1FMPT60HSDNZFP9XG65 type journalArticle.
- 01JH3CD1FMPT60HSDNZFP9XG65 hasPart 01JH3CFFD24Y9HM0SDPRREEDVM.pdf.
- 01JH3CD1FMPT60HSDNZFP9XG65 hasPart 01JHQWQCBK09Y0P31SPTPB2WW6.pdf.
- 01JH3CD1FMPT60HSDNZFP9XG65 subject "Medicine and Health Sciences".
- 01JH3CD1FMPT60HSDNZFP9XG65 subject "Social Sciences".
- 01JH3CD1FMPT60HSDNZFP9XG65 doi "10.1016/j.bbr.2025.115416".
- 01JH3CD1FMPT60HSDNZFP9XG65 issn "0166-4328".
- 01JH3CD1FMPT60HSDNZFP9XG65 issn "1872-7549".
- 01JH3CD1FMPT60HSDNZFP9XG65 volume "481".
- 01JH3CD1FMPT60HSDNZFP9XG65 abstract "Working memory is crucial for daily life and is often impaired in neuropsychiatric conditions. Attempts to enhance it using transcranial direct current stimulation (tDCS) have shown mixed results, possibly due to large inter-individual variability. This study assessed whether baseline regional brain volume was associated with working memory performance following tDCS. Healthy participants were randomly assigned to three bilateral tDCS protocols (sham, 1.5 mA, and 3 mA) over the dorsolateral prefrontal cortex (dlPFC) (anode-left, cathode-right) for 20 minutes, in a within-subjects design with a 2-week interval, followed by emotional and non-emotional 3-back tasks. Baseline volumetric data were used to extract gray matter volumes of defined regions of interest; the dlPFC, the medial PFC (mPFC), and the posterior cingulate cortex (PCC) bilaterally. Data from thirty-nine participants (69.2 % female, mean age: 24.56 years) across 112 tDCS sessions were analyzed. Findings revealed no significant association between working memory performance post sham-tDCS and gray matter volume. However, larger baseline cortical volumes across all regions were associated with slower reaction times and lower accuracy for the non-emotional task at 1.5 mA, whereas non-significant results were observed at 3 mA. For the emotional task, only a significant association for reaction time after 3 mA and left dlPFC and right PCC were found. Findings highlight not only the association between individual baseline gray matter, but also the impact of methodological choices, such as current intensity and outcome, on the effect of tDCS. Future research should aim to further explore individual variability and methodological factors to deepen our understanding of the mechanisms underlying tDCS.".
- 01JH3CD1FMPT60HSDNZFP9XG65 author 1CD07436-F0EE-11E1-A9DE-61C894A0A6B4.
- 01JH3CD1FMPT60HSDNZFP9XG65 author 3376AFFC-F0EE-11E1-A9DE-61C894A0A6B4.
- 01JH3CD1FMPT60HSDNZFP9XG65 author 63303dd4-4cb1-11ec-81a3-c62108cec111.
- 01JH3CD1FMPT60HSDNZFP9XG65 author F7FB3A6A-F0ED-11E1-A9DE-61C894A0A6B4.
- 01JH3CD1FMPT60HSDNZFP9XG65 author urn:uuid:140b31c3-a0d0-4e3e-91f8-1209c8bc2a8e.
- 01JH3CD1FMPT60HSDNZFP9XG65 author urn:uuid:c4bbac2d-91cd-47af-bf61-879bd7594b46.
- 01JH3CD1FMPT60HSDNZFP9XG65 author urn:uuid:d4118c44-c11c-4292-a6a7-344549cd3fe7.
- 01JH3CD1FMPT60HSDNZFP9XG65 dateCreated "2025-01-08T16:36:43Z".
- 01JH3CD1FMPT60HSDNZFP9XG65 dateModified "2025-01-17T08:17:14Z".
- 01JH3CD1FMPT60HSDNZFP9XG65 name "Baseline gray matter volume associates with working memory performance after prefrontal transcranial direct current stimulation".
- 01JH3CD1FMPT60HSDNZFP9XG65 pagination urn:uuid:b514421e-b46f-4780-b6b2-a4a4cc876dec.
- 01JH3CD1FMPT60HSDNZFP9XG65 sameAs LU-01JH3CD1FMPT60HSDNZFP9XG65.
- 01JH3CD1FMPT60HSDNZFP9XG65 sourceOrganization urn:uuid:5daa250e-4f3e-4112-bf95-13e9aa4998fe.
- 01JH3CD1FMPT60HSDNZFP9XG65 sourceOrganization urn:uuid:b77707d0-3396-4f9b-9a1c-71f59fad0f0f.
- 01JH3CD1FMPT60HSDNZFP9XG65 type A1.