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- 01JHG0EZ2D5WFEVCDA8GQMKCGA classification A1.
- 01JHG0EZ2D5WFEVCDA8GQMKCGA date "2025".
- 01JHG0EZ2D5WFEVCDA8GQMKCGA language "eng".
- 01JHG0EZ2D5WFEVCDA8GQMKCGA type journalArticle.
- 01JHG0EZ2D5WFEVCDA8GQMKCGA hasPart 01JJPKDFG98VHH7JYKA6JEBZQ1.pdf.
- 01JHG0EZ2D5WFEVCDA8GQMKCGA hasPart 01JJPKENZEHD6XJ6PRJV1MCMP2.pdf.
- 01JHG0EZ2D5WFEVCDA8GQMKCGA hasPart urn:uuid:c2c76324-6ab1-4836-893f-67d1919c9cec.
- 01JHG0EZ2D5WFEVCDA8GQMKCGA subject "Biology and Life Sciences".
- 01JHG0EZ2D5WFEVCDA8GQMKCGA doi "10.1016/j.biortech.2024.132006".
- 01JHG0EZ2D5WFEVCDA8GQMKCGA issn "0960-8524".
- 01JHG0EZ2D5WFEVCDA8GQMKCGA issn "1873-2976".
- 01JHG0EZ2D5WFEVCDA8GQMKCGA volume "419".
- 01JHG0EZ2D5WFEVCDA8GQMKCGA abstract "Bio-based long-chain dicarboxylic acids (LCDAs) are in high demand in the polymer industry. These compounds have diverse applications as building blocks for polymers with distinct features, which lead to a fast-growing global LCDA market. However, bio-based LCDA production is currently limited in Europe as established processes are using the pathogenic yeast, Candida tropicalis. Therefore, this study aimed to establish safe and sustainable LCDA production using an industrially relevant non-pathogenic yeast, Starmerella bombicola. The metabolic network was successfully controlled to channel fatty acids from rapeseed oil into the omega-oxidation for the high production of LCDAs. Importantly, the engineered yeast strain produced 5.5 g/l of total LCDAs in shake flasks. Furthermore, pH optimization of the bioprocess resulted in a significant improvement of the total LCDA titer up to 117.8 g/l. The outcomes strongly demonstrate that S. bombicola can serve as a safe and efficient platform microorganism for industrial LCDA production.".
- 01JHG0EZ2D5WFEVCDA8GQMKCGA author 5dca9e62-c99a-11ec-a040-8f876a977093.
- 01JHG0EZ2D5WFEVCDA8GQMKCGA author F72F990A-F0ED-11E1-A9DE-61C894A0A6B4.
- 01JHG0EZ2D5WFEVCDA8GQMKCGA author urn:uuid:0b80d8cd-be68-48e9-a065-5e018389de2c.
- 01JHG0EZ2D5WFEVCDA8GQMKCGA author urn:uuid:e196dedc-f55f-49a0-8926-b587e6690359.
- 01JHG0EZ2D5WFEVCDA8GQMKCGA dateCreated "2025-01-13T14:18:10Z".
- 01JHG0EZ2D5WFEVCDA8GQMKCGA dateModified "2025-01-28T14:02:10Z".
- 01JHG0EZ2D5WFEVCDA8GQMKCGA name "Turning the non-pathogenic yeast Starmerella bombicola into a powerful long-chain dicarboxylic acid production host".
- 01JHG0EZ2D5WFEVCDA8GQMKCGA pagination urn:uuid:521f4fab-a815-43ee-b14c-b759f774a824.
- 01JHG0EZ2D5WFEVCDA8GQMKCGA sameAs LU-01JHG0EZ2D5WFEVCDA8GQMKCGA.
- 01JHG0EZ2D5WFEVCDA8GQMKCGA sourceOrganization urn:uuid:c525367f-dfd0-4ffa-884b-7d3be8c45c64.
- 01JHG0EZ2D5WFEVCDA8GQMKCGA type A1.