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- 01JHT9G0V5AJT4FR6WSSDF3YSK classification A1.
- 01JHT9G0V5AJT4FR6WSSDF3YSK date "2024".
- 01JHT9G0V5AJT4FR6WSSDF3YSK language "eng".
- 01JHT9G0V5AJT4FR6WSSDF3YSK type journalArticle.
- 01JHT9G0V5AJT4FR6WSSDF3YSK hasPart 01JHTEGJVR5MS7P7BE6SGSQ3CJ.pdf.
- 01JHT9G0V5AJT4FR6WSSDF3YSK subject "Biology and Life Sciences".
- 01JHT9G0V5AJT4FR6WSSDF3YSK subject "Earth and Environmental Sciences".
- 01JHT9G0V5AJT4FR6WSSDF3YSK doi "10.1093/ismejo/wrae251".
- 01JHT9G0V5AJT4FR6WSSDF3YSK issn "1751-7362".
- 01JHT9G0V5AJT4FR6WSSDF3YSK issn "1751-7370".
- 01JHT9G0V5AJT4FR6WSSDF3YSK issue "1".
- 01JHT9G0V5AJT4FR6WSSDF3YSK volume "18".
- 01JHT9G0V5AJT4FR6WSSDF3YSK abstract "Quorum sensing (QS) inhibition is a promising novel approach to control bacterial infections. However, it is not clear whether QS inhibition will impose selective pressure for the spread of resistance against QS inhibition in pathogen populations. Previous research tried to answer this question by using synthetic growth media, and this revealed that whether or not resistance will spread completely depends on the environment in which it is studied. Therefore, the spread of resistance should be studied in the environment where it ultimately matters: in vivo during infection of a host. Here, using QS inhibitor-susceptible and -resistant mimics, we show that resistance to QS inhibition does not spread in host-associated populations of Vibrio campbellii during up to 35 cycles of infection and transmission if the initial frequency of the resistance is low in the pathogen population, whereas it further increases to 100% if it is already prevalent. However, even in the latter case, the resistance spreads at a slower pace than resistance to antibiotics spreads under the same conditions.".
- 01JHT9G0V5AJT4FR6WSSDF3YSK author 3BC3AAC0-F0EE-11E1-A9DE-61C894A0A6B4.
- 01JHT9G0V5AJT4FR6WSSDF3YSK author F6F08698-F0ED-11E1-A9DE-61C894A0A6B4.
- 01JHT9G0V5AJT4FR6WSSDF3YSK dateCreated "2025-01-17T14:08:26Z".
- 01JHT9G0V5AJT4FR6WSSDF3YSK dateModified "2025-01-17T15:40:04Z".
- 01JHT9G0V5AJT4FR6WSSDF3YSK name "Weak selection for resistance to quorum sensing inhibition during multiple host infection cycles".
- 01JHT9G0V5AJT4FR6WSSDF3YSK pagination urn:uuid:80f8eb91-dbb9-45b4-b731-abd0def96741.
- 01JHT9G0V5AJT4FR6WSSDF3YSK sameAs LU-01JHT9G0V5AJT4FR6WSSDF3YSK.
- 01JHT9G0V5AJT4FR6WSSDF3YSK sourceOrganization urn:uuid:a26415df-8c26-4984-8be7-0c5c78c0b4fd.
- 01JHT9G0V5AJT4FR6WSSDF3YSK type A1.