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- aggregation classification "A1".
- aggregation creator B172821.
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- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2010".
- aggregation format "application/pdf".
- aggregation hasFormat 1008286.bibtex.
- aggregation hasFormat 1008286.csv.
- aggregation hasFormat 1008286.dc.
- aggregation hasFormat 1008286.didl.
- aggregation hasFormat 1008286.doc.
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- aggregation hasFormat 1008286.txt.
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- aggregation hasFormat 1008286.yaml.
- aggregation isPartOf urn:issn:0027-8424.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Biology and Life Sciences".
- aggregation title "Arabidopsis PIS1 encodes the ABCG37 transporter of auxinic compounds including the auxin precursor indole-3-butyric acid".
- aggregation abstract "Differential distribution of the plant hormone auxin within tissues mediates a variety of developmental processes. Cellular auxin levels are determined by metabolic processes including synthesis, degradation, and (de)conjugation, as well as by auxin transport across the plasma membrane. Whereas transport of free auxins such as naturally occurring indole-3-acetic acid (IAA) is well characterized, little is known about the transport of auxin precursors and metabolites. Here, we identify a mutation in the ABCG37 gene of Arabidopsis that causes the polar auxin transport inhibitor sensitive1 (pis1) phenotype manifested by hypersensitivity to auxinic compounds. ABCG37 encodes the pleiotropic drug resistance transporter that transports a range of synthetic auxinic compounds as well as the endogenous auxin precursor indole-3-butyric acid (IBA), but not free IAA. ABCG37 and its homolog ABCG36 act redundantly at outermost root plasma membranes and, unlike established IAA transporters from the PIN and ABCB families, transport IBA out of the cells. Our findings explore possible novel modes of regulating auxin homeostasis and plant development by means of directional transport of the auxin precursor IBA and presumably also other auxin metabolites.".
- aggregation authorList BK424598.
- aggregation endPage "10753".
- aggregation issue "23".
- aggregation startPage "10749".
- aggregation volume "107".
- aggregation aggregates 2990074.
- aggregation isDescribedBy 1008286.
- aggregation similarTo pnas.1005878107.
- aggregation similarTo LU-1008286.