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- aggregation classification "A1".
- aggregation creator person.
- aggregation creator person.
- aggregation date "2010".
- aggregation format "application/pdf".
- aggregation hasFormat 1018431.bibtex.
- aggregation hasFormat 1018431.csv.
- aggregation hasFormat 1018431.dc.
- aggregation hasFormat 1018431.didl.
- aggregation hasFormat 1018431.doc.
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- aggregation hasFormat 1018431.yaml.
- aggregation isPartOf urn:issn:0027-8424.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Biology and Life Sciences".
- aggregation title "Auxin regulates distal stem cell differentiation in Arabidopsis roots".
- aggregation abstract "The stem cell niche in the root meristem is critical for the development of the plant root system. The plant hormone auxin acts as a versatile trigger in many developmental processes, including the regulation of root growth, but its role in the control of the stem cell activity remains largely unclear. Here we show that local auxin levels, determined by biosynthesis and intercellular transport, mediate maintenance or differentiation of distal stem cells in the Arabidopsis thaliana roots. Genetic analysis shows that auxin acts upstream of the major regulators of the stem cell activity, the homeodomain transcription factor WOX5, and the AP-2 transcription factor PLETHORA. Auxin signaling for differentiation of distal stem cells requires the transcriptional repressor IAA17/AXR3 as well as the ARF10 and ARF16 auxin response factors. ARF10 and ARF16 activities repress the WOX5 transcription and restrict it to the quiescent center, where WOX5, in turn, is needed for the activity of PLETHORA. Our investigations reveal that long-distance auxin signals act upstream of the short-range network of transcriptional factors to mediate the differentiation of distal stem cells in roots.".
- aggregation authorList BK692524.
- aggregation endPage "12051".
- aggregation issue "26".
- aggregation startPage "12046".
- aggregation volume "107".
- aggregation aggregates 2989688.
- aggregation isDescribedBy 1018431.
- aggregation similarTo pnas.1000672107.
- aggregation similarTo LU-1018431.