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- aggregation classification "A1".
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2010".
- aggregation format "application/pdf".
- aggregation hasFormat 1019453.bibtex.
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- aggregation isPartOf urn:issn:1474-1733.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Biology and Life Sciences".
- aggregation title "The X chromosome in immune functions: when a chromosome makes the difference".
- aggregation abstract "In response to various immune challenges, females show better survival than males; the X chromosome has an important role in this immunological advantage. X chromosome-linked diseases are usually restricted to males, who have only one copy of the X chromosome; however, females are more prone to autoimmune diseases, and the X chromosome may be involved in the breakdown of self tolerance. Several hypotheses have been proposed in recent years that support a role for the X chromosome in shaping autoimmune responses. Here, we review the main mechanisms responsible for increased immune activity in females. This provides a survival advantage in the face of pathogenic insult but can also enhance the susceptibility of females to autoimmunity.".
- aggregation authorList BK680233.
- aggregation endPage "604".
- aggregation issue "8".
- aggregation startPage "594".
- aggregation volume "10".
- aggregation aggregates 2937402.
- aggregation isDescribedBy 1019453.
- aggregation similarTo nri2815.
- aggregation similarTo LU-1019453.