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- aggregation classification "A1".
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- aggregation creator person.
- aggregation creator person.
- aggregation date "2011".
- aggregation format "application/pdf".
- aggregation hasFormat 1078698.bibtex.
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- aggregation isPartOf urn:issn:1078-0998.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Boosting the hypoxia-induced adaptive response in inflammatory bowel disease: a novel concept of treatment".
- aggregation abstract "As cells critically depend on oxygen for function and survival, inadequate cellular oxygenation is a major factor in the pathogenesis of a number of life-threatening diseases. Not surprisingly, cells share adaptive mechanisms to protect them against low-oxygen conditions. The recent discovery of a new family of oxygen-dependent hydroxylases has markedly increased the understanding of these adaptive processes, which in turn has led to the identification of new therapeutic targets for the treatment of conditions associated with enhanced hypoxia, such as a number of vascular and inflammatory diseases. This mini-review focuses on inhibition of hydroxylases as a potential novel treatment option for inflammatory bowel disease. Current knowledge, as well as future directions, are summarized and discussed.".
- aggregation authorList BK934226.
- aggregation endPage "2022".
- aggregation issue "9".
- aggregation startPage "2019".
- aggregation volume "17".
- aggregation aggregates 2093536.
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- aggregation similarTo ibd.21589.
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