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- aggregation classification "A1".
- aggregation creator B331178.
- aggregation creator B331179.
- aggregation creator B331180.
- aggregation creator B331181.
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- aggregation creator person.
- aggregation date "2010".
- aggregation format "application/pdf".
- aggregation hasFormat 1091827.bibtex.
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- aggregation isPartOf urn:issn:0268-9146.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Biology and Life Sciences".
- aggregation title "Genome-wide SNP association-based localization of a dwarfism gene in Friesian dwarf horses".
- aggregation abstract "The recent completion of the horse genome and commercial availability of an equine SNP genotyping array has facilitated the mapping of disease genes. We report putative localization of the gene responsible for dwarfism, a trait in Friesian horses that is thought to have a recessive mode of inheritance, to a 2- MB region of chromosome 14 using just 10 affected animals and 10 controls. We successfully genotyped 34 429 SNPs that were tested for association with dwarfism using chi-square tests. The most significant SNP in our study, BIEC2-239376 (P-2df = 4.54 x 10-5, P-rec = 7.74 x 10-6), is located close to a gene implicated in human dwarfism. Fine-mapping and resequencing analyses did not aid in further localization of the causative variant, and replication of our findings in independent sample sets will be necessary to confirm these results.".
- aggregation authorList BK624672.
- aggregation endPage "7".
- aggregation issue "suppl. 2".
- aggregation startPage "2".
- aggregation volume "41".
- aggregation aggregates 1091841.
- aggregation isDescribedBy 1091827.
- aggregation similarTo j.1365-2052.2010.02091.x.
- aggregation similarTo LU-1091827.