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- aggregation classification "A1".
- aggregation creator B52155.
- aggregation creator B52156.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "1999".
- aggregation format "application/pdf".
- aggregation hasFormat 112719.bibtex.
- aggregation hasFormat 112719.csv.
- aggregation hasFormat 112719.dc.
- aggregation hasFormat 112719.didl.
- aggregation hasFormat 112719.doc.
- aggregation hasFormat 112719.json.
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- aggregation hasFormat 112719.txt.
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- aggregation hasFormat 112719.yaml.
- aggregation isPartOf urn:issn:0960-7412.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Biology and Life Sciences".
- aggregation title "Specific checkpoints regulate plant cell cycle progression in response to oxidative stress".
- aggregation abstract "The effects of oxidative stress on plant cell cycle progression were studied both in cell suspensions and in planta. Oxidative stress of variable severity was imposed by the addition of different concentrations of the methyl-quinone, menadione, into the growth media. In cell suspensions, flow cytometry analyses demonstrated that low concentrations (20-50 mu M) of menadione impaired the G1/S transition, slowed DNA replication, and delayed the entry into mitosis. Furthermore, cells in G1 were more sensitive to menadione-mediated oxidative stress than cells in S phase. Cell cycle arrest was associated with an inhibition of the activity of cyclin-dependent kinases, cell cycle gene expression, and a concomitant activation of stress genes. Menadione-mediated oxidative stress was shown to have very similar effects on tobacco plants, suggesting that a general regulation mechanism takes place in plants. These results define an oxidative stress checkpoint pathway that modulates both the expression of the core cell cycle genes and oxidative defence genes. Redox sensing could be of key importance in controlling cell cycle progression in environmental stress conditions.".
- aggregation authorList BK132910.
- aggregation endPage "656".
- aggregation issue "6".
- aggregation startPage "647".
- aggregation volume "17".
- aggregation aggregates 4161294.
- aggregation isDescribedBy 112719.
- aggregation similarTo j.1365-313X.1999.00413.x.
- aggregation similarTo LU-112719.