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- aggregation classification "A2".
- aggregation creator B334946.
- aggregation creator B334947.
- aggregation creator person.
- aggregation date "2011".
- aggregation format "application/pdf".
- aggregation hasFormat 1150624.bibtex.
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- aggregation isPartOf urn:issn:1758-3799.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Dysplasia (or intraepithelial neoplasia) and neoplasia without dysplasia in the digestive tract".
- aggregation abstract "cancer of the digestive tract is a major medical problem associated with considerable morbidity and mortality. Surgery remains the only curative treatment. Despite the development of new chemotherapeutic and radiotherapy regimens, the prognosis of advanced cancer remains limited. early detection and treatment are essential in the management of these cancers. early detection relies on the identification of precancerous or premalignant lesions, i.e. lesions that do not yet show features of invasion. These have been called dysplasia and can be identified by morphology. Three factors have an impact on the subsequent therapeutic strategy: macroscopy results, type and number of biopsies and histology results. A lesion may be either flat or elevated. Biopsies can be obtained randomly or in targeted lesions and the ratio of positive biopsies to total number of samples taken is an important determinant in the risk of finding a malignancy. Specific cytological and architectural features allow distinction between low- and high-grade lesions, but not all neoplastic lesions show these features.".
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