Matches in UGent Biblio for { <https://biblio.ugent.be/publication/1193509#aggregation> ?p ?o. }
Showing items 1 to 40 of
40
with 100 items per page.
- aggregation classification "A1".
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2010".
- aggregation format "application/pdf".
- aggregation hasFormat 1193509.bibtex.
- aggregation hasFormat 1193509.csv.
- aggregation hasFormat 1193509.dc.
- aggregation hasFormat 1193509.didl.
- aggregation hasFormat 1193509.doc.
- aggregation hasFormat 1193509.json.
- aggregation hasFormat 1193509.mets.
- aggregation hasFormat 1193509.mods.
- aggregation hasFormat 1193509.rdf.
- aggregation hasFormat 1193509.ris.
- aggregation hasFormat 1193509.txt.
- aggregation hasFormat 1193509.xls.
- aggregation hasFormat 1193509.yaml.
- aggregation isPartOf urn:issn:0342-4642.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Impact of organ dysfunction on mortality in ICU patients with hematologic malignancies".
- aggregation abstract "To compare evolution in organ dysfunction (OD) between hematologic malignancy patients with and without bacterial infection (BI) precipitating intensive care unit (ICU) admission, and to assess its impact on mortality. Retrospective analysis of prospectively collected data was performed. Sequential Organ Failure Assessment (SOFA) scores from day 1 to 5 were calculated in all consecutive hematologic malignancy patients admitted to the ICU (2000-2006). Patients were categorized according to the presence or absence, the diagnostic certainty, and the site of BI. Of the 344 patients admitted, 258 were still in the ICU at day 3 and 164 at day 5. Patients admitted because of BI had more severe OD on day 1 (SOFA 9.7 +/- A 4.0 vs. 8.4 +/- A 4.0, p = 0.008) but a more rapidly reversible OD within the first 3 days (Delta SOFA -1.12 +/- A 3.10 vs. 0.03 +/- A 3.40, p = 0.013) and a lower in-hospital (43.2% vs. 62.9%, p < 0.001) and 6-month mortality (52.1% vs. 71.7%, p < 0.001) than patients with other complications. In a multivariate analysis, BI remained associated with a lower risk of death (OR 0.20, 95% CI 0.1-0.4, p < 0.001) even after adjustment for the SOFA on day 1 (OR 1.36, 95% CI 1.22-1.52, p < 0.001) and the Delta SOFA (OR 1.48, 95% CI 1.29-1.68, p < 0.001). These findings remained significant regardless of the site and the diagnostic certainty of BI. BI is associated with a more severe initial but a more rapidly reversible OD and a subsequent lower mortality compared to other complications in ICU patients with hematologic malignancies. These findings further support the recommendation that these patients should certainly benefit from advanced life support, and in the case of an uncertain long-term prognosis due to the underlying malignancy, at least from a 3-day ICU trial.".
- aggregation authorList BK630715.
- aggregation endPage "1750".
- aggregation issue "10".
- aggregation startPage "1744".
- aggregation volume "36".
- aggregation aggregates 1260338.
- aggregation isDescribedBy 1193509.
- aggregation similarTo s00134-010-1903-8.
- aggregation similarTo LU-1193509.