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- aggregation classification "A1".
- aggregation creator B333290.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2011".
- aggregation format "application/pdf".
- aggregation hasFormat 1222947.bibtex.
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- aggregation hasFormat 1222947.didl.
- aggregation hasFormat 1222947.doc.
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- aggregation isPartOf urn:issn:0934-0874.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Donor haptoglobin phenotype determines outcome following liver transplantation".
- aggregation abstract "Haptoglobin (Hp) is a polymorphic plasma protein with multiple functions defined by three major phenotypes (Hp 1-1, Hp 2-1, and Hp 2-2). In this article, the effects of the donor Hp phenotype (determined by starch gel electrophoresis) on the outcome and the iron status after liver transplantation were investigated. A total of 450 liver transplant patients were enrolled in this study with a median follow-up of 37 months. Kaplan-Meier and Cox regression survival analyses showed a significantly worse graft survival for liver transplantation cases with an Hp 2-2 donor phenotype, which was associated with an increased mortality rate in this group. In male patients, the Hp 2-2 phenotype was associated with higher serum ferritin concentrations, which may be linked to the significantly increased likelihood of infectious complications in this phenotype. Liver transplant patients with Hp 1-1 and Hp 2-1 grafts had a better outcome probability than recipients of an Hp 2-2 graft, which may be explained by differences in iron metabolism induced by the Hp genotype of the graft.".
- aggregation authorList BK628194.
- aggregation endPage "626".
- aggregation issue "6".
- aggregation startPage "619".
- aggregation volume "24".
- aggregation aggregates 1223007.
- aggregation aggregates 1223614.
- aggregation isDescribedBy 1222947.
- aggregation similarTo j.1432-2277.2011.01246.x.
- aggregation similarTo LU-1222947.