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- aggregation classification "A1".
- aggregation creator B416565.
- aggregation creator B416566.
- aggregation creator B416567.
- aggregation creator B416568.
- aggregation creator B416569.
- aggregation creator person.
- aggregation date "2010".
- aggregation format "application/pdf".
- aggregation hasFormat 1261826.bibtex.
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- aggregation hasFormat 1261826.txt.
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- aggregation hasFormat 1261826.yaml.
- aggregation isPartOf urn:issn:1824-4661.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "FDG uptake in lymph-nodes of HIV plus and tuberculosis patients: implications for cancer staging".
- aggregation abstract "Aim. The incidence of non-AIDS-related cancers (NADCs) in the AIDS-population has surpassed that of the general population. HIV significantly increases an individual's chances of reactivation of latent tuberculosis (TB) infection and progression to active TB disease. Both HIV, TB and CA present with increased FDG uptake in involved lymph nodes (LNs). The aim of this study was to assess the existence of quantitative differences in FDG uptake by lymph nodes in HIV+/TB-/CA- patients, TB+/HIV-/CA-, TB+/HIV+/CA-patients and HIV-/TB-/CA+ patients. Methods. Sixteen consecutive referred patients suffering from HIV-1, 21 suffering from HIV-1 and TB and 16 suffering from TB alone were prospectively included. In addition, 30 consecutively referred, previously untreated, HIV and TB negative cancer patients were included. All patients underwent FDG PET imaging. Mean standardized uptake values (SUV mean values) were obtained for involved lymph nodes using region growing and a threshold of 30% in all patients. Results obtained were compared using non-parametric statistics. Results. SUVmean values of involved LNs of HIV+/TB+/ CA- patients were significantly higher than SUVmean values of involved LNs of HIV-/TB+/CA- patients and HIV+/ TB-/CA patients (P < 0.05). Also, SUVmean values of involved LNs of HIV-/TB-/CA+ patients were significantly higher than SUVmean values of involved LNs of HIV+/ TB-/CA- patients. HIV+/TB+/CA- patients presented with a significantly higher number of sites of LN involvement when compared to the HIV+/TB-/CA- patient group. Conclusion. FDG PET is not useful for assessing malignant lymph node involvement in HIV+, TB+ or HIV+/TB+ patients.".
- aggregation authorList BK736160.
- aggregation endPage "703".
- aggregation issue "6".
- aggregation startPage "698".
- aggregation volume "54".
- aggregation aggregates 1266160.
- aggregation isDescribedBy 1261826.
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