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- aggregation classification "A1".
- aggregation creator B176406.
- aggregation creator B176407.
- aggregation creator B176408.
- aggregation creator B176409.
- aggregation creator B176410.
- aggregation creator B176411.
- aggregation creator B176412.
- aggregation creator B176413.
- aggregation creator B176414.
- aggregation creator B176415.
- aggregation creator B176416.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2011".
- aggregation format "application/pdf".
- aggregation hasFormat 1314195.bibtex.
- aggregation hasFormat 1314195.csv.
- aggregation hasFormat 1314195.dc.
- aggregation hasFormat 1314195.didl.
- aggregation hasFormat 1314195.doc.
- aggregation hasFormat 1314195.json.
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- aggregation hasFormat 1314195.txt.
- aggregation hasFormat 1314195.xls.
- aggregation hasFormat 1314195.yaml.
- aggregation isPartOf urn:issn:0194-911X.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Ethnic differences in arterial wave reflections and normative equations for augmentation index".
- aggregation abstract "Data regarding ethnic differences in wave reflections, which markedly affect the central pressure profile, are very limited. Furthermore, because age, heart rate, and body height are strong determinants of augmentation index, relating single measurements to normative data (in which augmentation index values correspond with average population values of its determinants) is challenging. We studied subject-level data from 10 550 adults enrolled in large population-based studies. In a healthy reference sample (n = 3497), we assessed ethnic differences in augmentation index (ratio of second/first systolic peaks) and generated equations for adjusted z scores, allowing for a standardized comparison between individual augmentation index measurements and the normative population mean from subjects of the same age, sex, ethnic population, body height, and heart rate. After adjustment for age, body height, heart rate, and mean arterial pressure, African blacks (women: 154%; men: 138%) and Andean Hispanics (women: 152%; men: 133%) demonstrated higher central (aortic) augmentation index values than British whites (women: 140%; men: 128%), whereas American Indians (women: 133%; men: 122%) demonstrated lower augmentation index (all P < 0.0001), without significant differences between Chinese and British whites. Similar results were found for radial augmentation index. Nonlinear ethnic/sex-specific equations for z scores were successfully generated to adjust individual augmentation index values for age, body height, and heart rate. Marked ethnic differences in augmentation index exist, which may contribute to ethnic differences in hypertensive organ damage. Our study provides normative data that can be used to complement the interpretation of individual hemodynamic assessments among men and women of various ethnic populations, after removing the effect of various physiological determinants. (Hypertension. 2011;57:1108-1116.). Online Data Supplement".
- aggregation authorList BK431553.
- aggregation endPage "U153".
- aggregation issue "6".
- aggregation startPage "1108".
- aggregation volume "57".
- aggregation aggregates 1315611.
- aggregation isDescribedBy 1314195.
- aggregation similarTo HYPERTENSIONAHA.110.166348.
- aggregation similarTo LU-1314195.