Matches in UGent Biblio for { <https://biblio.ugent.be/publication/137424#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B101410.
- aggregation creator B101411.
- aggregation creator B101412.
- aggregation creator B101413.
- aggregation creator B101414.
- aggregation creator person.
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- aggregation date "2001".
- aggregation hasFormat 137424.bibtex.
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- aggregation hasFormat 137424.yaml.
- aggregation isPartOf urn:issn:0269-9370.
- aggregation language "eng".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Vaginal lavage with chlorhexidine during labour to reduce mother-to-child HIV transmission: clinical trial in Mombasa, Kenya.".
- aggregation abstract "Objectives: To evaluate the effect of vaginal lavage with diluted chlorhexidine on mother-to child transmission of HIV (MTCT) in a breastfeeding population. Methods: This prospective clinical trial was conducted in a governmental hospital in Mombasa, Kenya. On alternating weeks, women were allocated to non-intervention or to intervention consisting of vaginal lavage with 120 ml 0.2% chlorhexidine, later increased to 0.4%, repeated every 3 h from admission to delivery. infants were tested for HIV by DNA polymerase chain reaction within 48 h and at 6 and 14 weeks of life. Results: Enrolment and follow-up data were available for 297 and 309 HIV-positive women, respectively, in the non-lavage and the lavage groups. There was no evidence of a difference in intrapartum MTCT (17.2 versus 15.9%, OR 0.9, 95% Cl 0.6-1.4) between the groups. Lavage solely before rupture of the membranes tended towards lower MTCT with chlorhexidine 0.2% (OR 0.6, 95% Cl 0.3-1.1), and even more with chlorhexidine 0.4% (OR 0.1, 95% Cl 0.0-0.9). Conclusion: The need remains for interventions reducing MTCT without HIV testing, often unavailable in countries with a high prevalence of HIV. Vaginal lavage with diluted chlorhexidine during delivery did not show a global effect on MTCT in our study. However, the data suggest that lavage before the membranes are ruptured might be associated with a reduction of MTCT, especially with higher concentrations of chlorhexidine.".
- aggregation authorList BK260445.
- aggregation endPage "396".
- aggregation issue "3".
- aggregation startPage "389".
- aggregation volume "15".
- aggregation isDescribedBy 137424.
- aggregation similarTo LU-137424.