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- aggregation classification "A1".
- aggregation creator B100424.
- aggregation creator B100425.
- aggregation creator B100426.
- aggregation creator B100427.
- aggregation creator person.
- aggregation date "2001".
- aggregation hasFormat 142156.bibtex.
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- aggregation isPartOf urn:issn:0398-7620.
- aggregation language "fre".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Relation entre l'uricémie et la mortalité totale, cardio-vasculaire et coronarienne dans un échantillon non-sélectionné de la population belge".
- aggregation abstract "Background: Despite more than 40 years of research on the prognostic value of hyperuricemia in relation to all-causes cardiovascular and coronary mortality, no clear consensus appears in the medical literature. Moreover, the observed relationship between hyperuricemia and the incidence of coronary heart disease mortality is related to gender. However, prospective studies including both genders are rare. Methods: A prospective study was conducted in a random sample of 5225 males and 4476 females from the Belgian population aged 25 to 74 years at the initial survey and followed for 10 years for all-causes and specific mortality. Results: The number of observed total, cardiovascular, and coronary heart disease deaths were 648 and 239, 150 and 225, and 96 and 51 in males and females respectively. At multivariate analysis, uricemia was significantly correlated with all-causes mortality in males whereas a tendency was observed in females. The same diverging association was observed for cardiovascular mortality. However, for coronary heart disease mortality, there was a very significant correlation only in females. Conclusions: Our findings confirm the observed gender-related differences in the relation of hyperuricemia with all-causes and coronary heart disease mortality. We propose possible pathogenic mechanisms concerning the relationship with coronary heart disease mortality observed only in females.".
- aggregation authorList BK258165.
- aggregation endPage "539".
- aggregation issue "6".
- aggregation startPage "531".
- aggregation volume "49".
- aggregation isDescribedBy 142156.
- aggregation similarTo LU-142156.