Matches in UGent Biblio for { <https://biblio.ugent.be/publication/165014#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B94777.
- aggregation creator B94778.
- aggregation creator B94779.
- aggregation creator B94780.
- aggregation creator B94781.
- aggregation creator person.
- aggregation date "2002".
- aggregation hasFormat 165014.bibtex.
- aggregation hasFormat 165014.csv.
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- aggregation hasFormat 165014.txt.
- aggregation hasFormat 165014.xls.
- aggregation hasFormat 165014.yaml.
- aggregation isPartOf urn:issn:0392-9590.
- aggregation language "eng".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Findings of the naftidrofuryl in quality of life (NIQOL) european study program".
- aggregation abstract "Background. We report in this paper the findings of a pooled analysis of 3 previously published studies undertaken in Germany, France and Belgium to assess the effects of naftidrofuryl on the quality of life of patients with intermittent claudication. Methods, A total of 754 patients were randomised in the 3 studies, 709 of whom (358 naftidrofuryl, 351 placebo) were available for the primary intention-to-treat analysis. The primary outcome variable was the change in the disease-related limitation of the quality of life as measured by the CLAU-S questionnaire. This instrument which has been validated in an international study, comprises 47 questions covering 5 dimensions: ''daily living'', ing'', ''pain'', ''social life'', ''disease specific anxiety''and ''mood''. Results. A multivariate analysis of covariance adjusted for baseline values, study effect and first order study treatment interaction, demonstrated the global superiority of naftidrofuryl over placebo (p<0.001). A separate covariance analysis for the 5 dimensions showed highly significant differences for ''daily living'', ''pain'', ''social life'' and ''mood'' (all p<0.01). Conclusions. In conclusion, this pooled analysis has shown that naftidrofuryl can significantly improve the quality of life of patients with intermittent claudication. These findings, taken together with evidence from previous studies that it improves treadmill walking distances, suggest that naftidrofuryl can play a useful role in the treatment of this condition.".
- aggregation authorList BK243805.
- aggregation endPage "27".
- aggregation issue "1".
- aggregation startPage "20".
- aggregation volume "21".
- aggregation isDescribedBy 165014.
- aggregation similarTo LU-165014.