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- aggregation classification "A1".
- aggregation creator person.
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- aggregation creator person.
- aggregation date "2000".
- aggregation format "application/pdf".
- aggregation hasFormat 172447.bibtex.
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- aggregation isPartOf urn:issn:0167-4412.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Biology and Life Sciences".
- aggregation title "Plants as bioreactors for protein production: avoiding the problem of transgene silencing".
- aggregation abstract "Plants are particularly attractive as large-scale production systems for proteins intended for therapeutical or industrial applications: they can be grown easily and inexpensively in large quantities that can be harvested and processed with the available agronomic infrastructures. The effective use of plants as bioreactors depends on the possibility of obtaining high protein accumulation levels that are stable during the life cycle of the transgenic plant and in subsequent generations. Silencing of the introduced transgenes has frequently been observed in plants, constituting a major commercial risk and hampering the general economic exploitation of plants as protein factories. Until now, the most efficient strategy to avoid transgene silencing involves careful design of the transgene construct and thorough analysis of transformants at the molecular level. Here, we focus on different aspects of the generation of transgenic plants intended for protein production and on their influence on the stability of heterologous gene expression.".
- aggregation authorList BK162400.
- aggregation endPage "359".
- aggregation issue "2-3".
- aggregation startPage "347".
- aggregation volume "43".
- aggregation aggregates 4150002.
- aggregation isDescribedBy 172447.
- aggregation similarTo A:1006464304199.
- aggregation similarTo LU-172447.