Matches in UGent Biblio for { <https://biblio.ugent.be/publication/1865359#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B384783.
- aggregation creator B384784.
- aggregation creator B384785.
- aggregation creator B384786.
- aggregation creator B384787.
- aggregation creator B384788.
- aggregation creator B384789.
- aggregation creator person.
- aggregation date "2011".
- aggregation format "application/pdf".
- aggregation hasFormat 1865359.bibtex.
- aggregation hasFormat 1865359.csv.
- aggregation hasFormat 1865359.dc.
- aggregation hasFormat 1865359.didl.
- aggregation hasFormat 1865359.doc.
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- aggregation hasFormat 1865359.txt.
- aggregation hasFormat 1865359.xls.
- aggregation hasFormat 1865359.yaml.
- aggregation isPartOf urn:issn:1439-6319.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Assessment of immune function after short-term administration of recombinant human growth hormone in healthy young males".
- aggregation abstract "Growth hormone (GH) is a commonly used drug aimed at improving sport performance. The aim of this study is to evaluate the immunomodulatory effects of short-term administration of recombinant GH (rhGH) in healthy young males. NK cell number, activity and phenotype, T cell number, CD4(+) (Th1/Th2) cytokine production of IL2, IL4, IL6, IL10, TNF-alpha and IFN-gamma and CD4(+)/CD8(+) ratio with particular attention to the possible correlation to IGF-I production were investigated. 30 males (27 +/- A 9 years) were randomly assigned to placebo (n = 15) or drug (rhGH) 1 mg/day groups (n = 15) with daily injection for 7 days. IGF-I plasma concentration and flow cytometry data were generated at baseline and days 8, 15, 22 and 29 post injection. Data analysis used General Linear Model with repeated measures, Bonferroni correction factor and significance at p a parts per thousand currency sign 0.05. Serum IGF-I levels (ng/mL) increased significantly (p a parts per thousand currency sign 0.01) on day 8 (0.48 +/- A 0.78) after injections compared to baseline (0.31 +/- A 0.07) and days 15 (0.33 +/- A 0.06), 22 (0.29 +/- A 0.05) and 29 (0.29 +/- A 0.06). A significant time effect was noted in IL10 secretion (pg/mL) from day 15 (P = 35.14 +/- A 19.93, rhGH = 26.63 +/- A 16.39) to days 22 (P = 61.32 +/- A 20.41, rhGH = 74.99 +/- A 46.91) and 29 (P = 101.98 +/- A 67.25, rhGH = 107.74; +/- A 122.58). There was no correlation between IGF-I and NK activity, phenotype or number along with T lymphocyte number, CD4(+)/CD8(+) ratio or Th1 and Th2 cytokine production. In conclusion, cytokine secretion spectrum was not affected by short-term rhGH administration in young males.".
- aggregation authorList BK695721.
- aggregation endPage "1312".
- aggregation issue "7".
- aggregation startPage "1307".
- aggregation volume "111".
- aggregation aggregates 1865408.
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- aggregation similarTo s00421-010-1756-4.
- aggregation similarTo LU-1865359.