Matches in UGent Biblio for { <https://biblio.ugent.be/publication/1982627#aggregation> ?p ?o. }
Showing items 1 to 61 of
61
with 100 items per page.
- aggregation classification "A1".
- aggregation creator B436769.
- aggregation creator B436770.
- aggregation creator B436771.
- aggregation creator B436772.
- aggregation creator B436773.
- aggregation creator B436774.
- aggregation creator B436775.
- aggregation creator B436776.
- aggregation creator B436777.
- aggregation creator B436778.
- aggregation creator B436779.
- aggregation creator B436780.
- aggregation creator B436781.
- aggregation creator B436782.
- aggregation creator B436783.
- aggregation creator B436784.
- aggregation creator B436785.
- aggregation creator B436786.
- aggregation creator B436787.
- aggregation creator B436788.
- aggregation creator B436789.
- aggregation creator B436790.
- aggregation creator B436791.
- aggregation creator B436792.
- aggregation creator B436793.
- aggregation creator B436794.
- aggregation creator B436795.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2011".
- aggregation format "application/pdf".
- aggregation hasFormat 1982627.bibtex.
- aggregation hasFormat 1982627.csv.
- aggregation hasFormat 1982627.dc.
- aggregation hasFormat 1982627.didl.
- aggregation hasFormat 1982627.doc.
- aggregation hasFormat 1982627.json.
- aggregation hasFormat 1982627.mets.
- aggregation hasFormat 1982627.mods.
- aggregation hasFormat 1982627.rdf.
- aggregation hasFormat 1982627.ris.
- aggregation hasFormat 1982627.txt.
- aggregation hasFormat 1982627.xls.
- aggregation hasFormat 1982627.yaml.
- aggregation isPartOf urn:issn:0028-0836.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Biology and Life Sciences".
- aggregation title "Ascaris suum draft genome".
- aggregation abstract "Parasitic diseases have a devastating, long-term impact on human health, welfare and food production worldwide. More than two billion people are infected with geohelminths, including the roundworms Ascaris (common roundworm), Necator and Ancylostoma (hookworms), and Trichuris (whipworm), mainly in developing or impoverished nations of Asia, Africa and Latin America(1). In humans, the diseases caused by these parasites result in about 135,000 deaths annually, with a global burden comparable with that of malaria or tuberculosis in disability-adjusted life years(1). Ascaris alone infects around 1.2 billion people and, in children, causes nutritional deficiency, impaired physical and cognitive development and, in severe cases, death(2). Ascaris also causes major production losses in pigs owing to reduced growth, failure to thrive and mortality(2). The Ascaris-swine model makes it possible to study the parasite, its relationship with the host, and ascariasis at the molecular level. To enable such molecular studies, we report the 273 mega-base draft genome of Ascaris suum and compare it with other nematode genomes. This genome has low repeat content (4.4%) and encodes about 18,500 protein-coding genes. Notably, the A. suum secretome (about 750 molecules) is rich in peptidases linked to the penetration and degradation of host tissues, and an assemblage of molecules likely to modulate or evade host immune responses. This genome provides a comprehensive resource to the scientific community and underpins the development of new and urgently needed interventions (drugs, vaccines and diagnostic tests) against ascariasis and other nematodiases.".
- aggregation authorList BK761627.
- aggregation endPage "U257".
- aggregation issue "7374".
- aggregation startPage "529".
- aggregation volume "479".
- aggregation aggregates 1988285.
- aggregation isDescribedBy 1982627.
- aggregation similarTo nature10553.
- aggregation similarTo LU-1982627.