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- aggregation classification "A2".
- aggregation creator person.
- aggregation date "2009".
- aggregation hasFormat 2006847.bibtex.
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- aggregation isPartOf urn:issn:1089-2532.
- aggregation language "eng".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Optimal versus suboptimal perfusion during cardiopulmonary bypass and the inflammatory response".
- aggregation abstract "Despite major improvements in perfusion techniques over the past 50 years, it is still not possible to formulate a clear definition of what is meant by optimal perfusion. In part this is due to the lack of sufficient evidence-based data and in part because of the complex pathophysiology that takes place during cardiac surgery with cardiopulmonary bypass. To find an answer we need to understand the exact mechanism of the inflammatory reaction triggered by the cardiopulmonary bypass. However, it is clear that further improvement of the cardiopulmonary bypass components alone will be sufficient. Only a combined strategy can further improve cardiopulmonary bypass-related morbidity and mortality. Such a combined strategy will embrace perfusion techniques as well as a pharmacological approach. It will also require a continuous monitoring of the microcirculation. The latter will not only allow to rapidly sense changes in the quality of perfusion but, even more important, also make it possible to intervene at the moment of deterioration. Recent research shows that such an approach has positive an impact on cardiopulmonary bypass-related morbidity postoperatively.".
- aggregation authorList BK486786.
- aggregation endPage "117".
- aggregation issue "2".
- aggregation startPage "113".
- aggregation volume "13".
- aggregation isDescribedBy 2006847.
- aggregation similarTo 1089253209337746.
- aggregation similarTo LU-2006847.