Matches in UGent Biblio for { <https://biblio.ugent.be/publication/2023249#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B222126.
- aggregation creator B222127.
- aggregation creator B222128.
- aggregation creator B222129.
- aggregation creator B222130.
- aggregation creator B222131.
- aggregation creator B222132.
- aggregation creator person.
- aggregation date "2011".
- aggregation format "application/pdf".
- aggregation hasFormat 2023249.bibtex.
- aggregation hasFormat 2023249.csv.
- aggregation hasFormat 2023249.dc.
- aggregation hasFormat 2023249.didl.
- aggregation hasFormat 2023249.doc.
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- aggregation hasFormat 2023249.txt.
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- aggregation hasFormat 2023249.yaml.
- aggregation isPartOf urn:issn:1932-6203.
- aggregation language "eng".
- aggregation rights "I have retained and own the full copyright for this publication".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "High prevalence of primary multidrug resistant tuberculosis in persons with no known risk factors".
- aggregation abstract "Introduction: In high multidrug resistant (MDR) tuberculosis (TB) prevalence areas, drug susceptibility testing (DST) at diagnosis is recommended for patients with risk factors for MDR. However, this approach might miss a substantial proportion of MDR-TB in the general population. We studied primary MDR in patients considered to be at low risk of MDR-TB in Lima, Peru. Methods: We enrolled new sputum smear-positive TB patients who did not report any MDR-TB risk factor: known exposure to a TB patient whose treatment failed or who died or who was known to have MDR-TB; immunosuppressive co-morbidities, ex prison inmates; prison and health care workers; and alcohol or drug abuse. A structured questionnaire was applied to all enrolled participants to confirm the absence of these factors and thus minimize underreporting. Sputum from all participants was cultured on Lowenstein-Jensen media and DST for first line drugs was performed using the 7H10 agar method. Results: Of 875 participants with complete data, 23.2% (203) had risk factors for MDR-TB elicited after enrolment. Among the group with no reported risk factors who had a positive culture, we found a 6.3% (95% CI 4.4-8.3) (37/584) rate of MDR-TB. In this group no epidemiological characteristics were associated with MDR-TB. Thus, in this group, multidrug resistance occurred in patients with no identifiable risk factors. Conclusions: We found a high rate of primary MDR-TB in a general population with no identifiable risk factors for MDR-TB. This suggests that in a high endemic area targeting patients for MDR-TB based on the presence of risk factors is an insufficient intervention.".
- aggregation authorList BK487039.
- aggregation issue "10".
- aggregation volume "6".
- aggregation aggregates 2023546.
- aggregation isDescribedBy 2023249.
- aggregation similarTo journal.pone.0026276.
- aggregation similarTo LU-2023249.