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- aggregation classification "A1".
- aggregation creator B130095.
- aggregation creator B130096.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "1993".
- aggregation format "application/pdf".
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- aggregation isPartOf urn:issn:0344-0338.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Biology and Life Sciences".
- aggregation title "Altered adrenocortical response under the influence of experimentally increased serum very long chain fatty acids in rats".
- aggregation abstract "C 26:0/C 22:0 ratio can be experimentally increased in serum of normal rats by oral administration of hexacosanoic acid (C 26:0) or of thioridazine, an inhibitor of peroxisomal beta-oxidation. This causes a decreased corticosterone response as well as decreased mobilization of cholesterol esters in zona fasciculata interna cells following ACTH administration. Zona fasciculata interna cells and their nuclei are enlarged and contain more Feulgen DNA in thioridazine-fed rats. The similarity of adrenocortical response to inhibition of peroxisomal beta-oxidation and to C 26:0 administration points to raised VLCFA as the common factor which is also operative in many peroxisomal diseases accompanied by adrenocortical function defects.".
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- aggregation issue "5".
- aggregation startPage "558".
- aggregation volume "189".
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