Matches in UGent Biblio for { <https://biblio.ugent.be/publication/2045297#aggregation> ?p ?o. }
Showing items 1 to 38 of
38
with 100 items per page.
- aggregation classification "A1".
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2012".
- aggregation format "application/pdf".
- aggregation hasFormat 2045297.bibtex.
- aggregation hasFormat 2045297.csv.
- aggregation hasFormat 2045297.dc.
- aggregation hasFormat 2045297.didl.
- aggregation hasFormat 2045297.doc.
- aggregation hasFormat 2045297.json.
- aggregation hasFormat 2045297.mets.
- aggregation hasFormat 2045297.mods.
- aggregation hasFormat 2045297.rdf.
- aggregation hasFormat 2045297.ris.
- aggregation hasFormat 2045297.txt.
- aggregation hasFormat 2045297.xls.
- aggregation hasFormat 2045297.yaml.
- aggregation isPartOf urn:issn:0903-1936.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "COPD is associated with reduced pulmonary interstitial expression of pentraxin-3".
- aggregation abstract "Pentraxin-3 (PTX3) is involved in antimicrobial defense, apoptotic cell clearance and extracellular matrix stability. As these processes are altered in Chronic Obstructive Pulmonary Disease (COPD), we aimed to investigate PTX3 expression in patients with this disease.PTX3 expression was quantified by immunohistochemical staining in lungs of never smokers, smokers without COPD and in patients with COPD GOLD stage I, II and III&IV. Messenger RNA (mRNA) expression was examined in total lung tissue by qRT-PCR. PTX3 concentration was measured in induced sputum and in plasma by ELISA.PTX3 is mainly localized in the interstitium of small airways and alveolar walls. There were no significant differences in pulmonary, sputum and plasma PTX3 expression between study groups. However, PTX3 expression in small airways correlated significantly with the forced expiratory volume in one second (r=0.35 ; p=0.004). In the alveolar walls, PTX3 expression correlated significantly with carbon monoxide transfer coefficient (r=0.28; p=0.04). In sputum, PTX3 levels were highly correlated with the number of neutrophils. Finally, systemic levels of PTX3 tended to be lower in severe COPD compared to mild COPD.In COPD, airflow limitation and reduced transfer coefficient for carbon monoxide are associated with lower pulmonary interstitial expression of PTX3.".
- aggregation authorList BK599997.
- aggregation endPage "838".
- aggregation issue "4".
- aggregation startPage "830".
- aggregation volume "39".
- aggregation aggregates 2045327.
- aggregation aggregates 2985966.
- aggregation isDescribedBy 2045297.
- aggregation similarTo 09031936.00138110.
- aggregation similarTo LU-2045297.