Matches in UGent Biblio for { <https://biblio.ugent.be/publication/2915916#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B281622.
- aggregation creator B281623.
- aggregation creator B281624.
- aggregation creator B281625.
- aggregation creator B281626.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2008".
- aggregation format "application/pdf".
- aggregation hasFormat 2915916.bibtex.
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- aggregation isPartOf urn:issn:0179-7158.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Longitudinal assessment of parotid function in patients receiving tomotherapy for head-and-neck cancer".
- aggregation abstract "Background and Purpose: Conventional radiotherapy is associated with high doses to the salivary glands which causes xerostomia and adverse effects on quality of life. The study aims to investigate the potential of helical tomotherapy (Hi-Art Tomotherapy (R)) to preserve parotid function in head-and-neck cancer patients. Patients and Methods: Seven consecutive patients treated with helical tomotherapy at the UZ Brussel, Belgium, were included. During planning, priority was attributed to planning target volume (PTV) coverage: >= 95% of the dose must be delivered to >= 95% of the PTV. Elective nodal regions received 54 Gy (1.8 Gy/fraction). A dose of 70.5 Gy (2.35 Gy/fraction) was prescribed to the primary tumor and pathologic lymph nodes = simultaneous integrated boost scheme. If possible, the mean parotid dose was kept below 26 Gy. Salivary gland function was assessed by technetiurn scintigraphy. Results: There was a significant dose-response relationship between mean parotid dose and functional recuperation. If the mean dose was kept < 31 Gy, a recuperation of 75% can be expected at 12 months. The authors equally observed a significant correlation between salivary excretion (SE) and the percentage of parotid gland receiving a dose < 26 Gy (V-26%). In order to preserve 75% of SE, 46% of the parotid volume should receive a dose < 26 Gy. Conclusion: With the use of helical tomography the parotid gland function can largely be preserved since the mean dose to the entire gland as well as glandular volume receiving > 26 Gy can be reduced.".
- aggregation authorList BK559546.
- aggregation endPage "405".
- aggregation issue "8".
- aggregation startPage "400".
- aggregation volume "184".
- aggregation aggregates 3030205.
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