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- aggregation classification "A1".
- aggregation creator B327165.
- aggregation creator B327166.
- aggregation creator person.
- aggregation date "1998".
- aggregation format "application/pdf".
- aggregation hasFormat 2916385.bibtex.
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- aggregation isPartOf urn:issn:0340-6997.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Gated SPET myocardial perfusion acquisition within 5 minutes using focussing collimators and a three-head gamma camera".
- aggregation abstract "Short acquisition protocols for gated single-photon emission tomography (SPET) myocardial perfusion imaging are desirable for sequential imaging to evaluate the myocardial response during pharmacological intervention. In this study a less than 5 min gated SPET acquisition protocol is proposed. Perfusion characteristics (defect severity) and left ventricular ejection fraction Introduction (LVEF), end-diastolic and end-systolic volumes (EDV, ESV), wall motion (WM) and wall thickening (WT) were calculated, checked for reproducibility and compared with data obtained using a standard gated SPET acquisition protocol. Gated SPET images were recorded in 20 patients starting 60 min after the administration of 925 MBq technetium-99m tetrofosmin at rest. The 5 min gated SPET studies were acquired with a three-head camera equipped with Cardiofocal collimators. This protocol was repeated twice. In addition gated SPET studies were acquired according to a standard protocol using parallel-hole collimators. The severity of perfusion defects was quantified on polar maps using the non-gated image data and a normal database. LVEF EDV, ESV, WM and WT were calculated from the gated images. The agreement between 5-min and standard gated SPET acquisitions was excellent for all investigated parameters. The reproducibility of repeated 5-min acquisitions for the quantification of perfusion defect severity was excellent (r=0.97). The agreement for segmental WT scores between repeated 5-min gated SPET acquisitions was good: kappa=0.71; major differences in segmental classification were observed in 2.5%. For WM a good agreement was found for segments with a tracer uptake greater than or equal to 30% of the maximum: kappa=0.65, major differences =7.7%. Excellent reproducibility was found for LVEF EDV and ESV measurements: r=0.97, 0.99 and 0.99, respectively. It is concluded that fast gated SPET perfusion studies acquired in less than 5 min yield accurate and reproducible measurements of myocardial perfusion and function (global and regional), In addition the results obtained with the 5-min gated SPET protocol correlate well with those obtained using a standard acquisition protocol.".
- aggregation authorList BK617198.
- aggregation endPage "593".
- aggregation issue "6".
- aggregation startPage "587".
- aggregation volume "25".
- aggregation aggregates 3131041.
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- aggregation similarTo s002590050259.
- aggregation similarTo LU-2916385.