Matches in UGent Biblio for { <https://biblio.ugent.be/publication/3063389#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B440548.
- aggregation creator B440549.
- aggregation creator B440550.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2013".
- aggregation format "application/pdf".
- aggregation hasFormat 3063389.bibtex.
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- aggregation hasFormat 3063389.didl.
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- aggregation isPartOf urn:issn:0928-4249.
- aggregation language "eng".
- aggregation rights "I have retained and own the full copyright for this publication".
- aggregation subject "Veterinary Sciences".
- aggregation title "Serological profiles in nursery piglets colonized with Staphylococcus aureus".
- aggregation abstract "At present, the immune response of pigs in relation to Staphylococcus aureus carriage is poorly understood. This study aimed at investigating the dynamics of the anti-staphylococcal humoral immune response in methicillin-susceptible S. aureus (MSSA)-positive piglets and at assessing the effect of the experimental introduction of a methicillin-resistant S. aureus (MRSA) Sequence Type (ST) 398 strain. Therefore, serum samples were collected at different times from 31 weaned piglets originating from four different sows. Twenty-four out of the 31 piglets were challenged with MRSA ST398. The serum samples were analysed for IgG antibodies to 39 S. aureus antigens, using a multiplex bead-based assay (xMAP technology, Luminex Corporation). Though antibody responses showed broad inter-individual variability, serological results appeared to be clustered by litter of origin. For most antigens, an age-related response was observed with an apparent increase in antibody titres directed against staphylococcal microbial surface components recognizing adhesive matrix molecules (MSCRAMMs), which have been shown to play a role in S. aureus colonization. In most animals, antibody titres directed against staphylococcal toxins or immune-modulating proteins decreased with age, possibly reflecting absence of bacterial invasion. The introduction of MRSA ST398 did not elicit a significant humoral immune reaction. This study describes, for the first time, the humoral immune response in weaned pigs colonized with S. aureus.".
- aggregation authorList BK768903.
- aggregation volume "44".
- aggregation aggregates 3212783.
- aggregation isDescribedBy 3063389.
- aggregation similarTo 1297-9716-44-4.
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