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- aggregation classification "A1".
- aggregation creator B867396.
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- aggregation creator person.
- aggregation date "2013".
- aggregation format "application/pdf".
- aggregation hasFormat 3071509.bibtex.
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- aggregation isPartOf urn:issn:0901-5027.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Bone apposition to laminin-1 coated implants: histologic and 3D evaluation".
- aggregation abstract "Laminin-1 has been reported as one of the factors responsible for the nucleation of calcium phosphates and, in vitro, has been reported to selectively recruit osteoprogenitors. This article focused on its in vivo effects, and evaluated the effect of laminin-1 local application on osseointegration. Polished cylindrical hydroxyapatite implants were coated with laminin-1 (test) and the bone responses in the rabbit tibiae after 2 and 4 weeks were evaluated and compared to the non-coated implants (control). Before the samples were processed for histological sectioning, they were three-dimensionally analysed with micro computed tomography (mu CT). Both evaluation methods were analysed with regards to bone area around the implant and bone to implant contact. From the histologic observation, new bone formation around the laminin-1 coated implant at 2 weeks seemed to have increased the amount of supporting bone around the implant, however, at 4 weeks, the two groups presented no notable differences. The two-dimensional and three-dimensional morphometric evaluation revealed that both histologic and three-dimensional analysis showed some tendency in favour of the test group implants, however there was no statistical significance between the test and control group results.".
- aggregation authorList BK1245205.
- aggregation endPage "682".
- aggregation issue "5".
- aggregation startPage "677".
- aggregation volume "42".
- aggregation aggregates 3071511.
- aggregation isDescribedBy 3071509.
- aggregation similarTo j.ijom.2012.11.008.
- aggregation similarTo LU-3071509.