Matches in UGent Biblio for { <https://biblio.ugent.be/publication/3090147#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B453291.
- aggregation creator B453292.
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- aggregation date "2012".
- aggregation format "application/pdf".
- aggregation hasFormat 3090147.bibtex.
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- aggregation isPartOf urn:issn:1744-683X.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Chemistry".
- aggregation title "Novel gelatin-PHEMA porous scaffolds for tissue engineering applications".
- aggregation abstract "In the present work, novel bicomponent polymeric hydrogels based on methacrylamide-modified gelatin (MAG) and 2-hydroxyethyl methacrylate (HEMA) have been prepared by cross-linking polymerization using photoinitiation. Five types of novel hydrogels have been prepared using different MAG/HEMA ratios between 1/0.5 and 1/10 w/w. Subsequently, porous scaffolds were obtained via a cryogenic treatment followed by freeze-drying. Physico-chemical measurements as well as in vitro degradation tests have been performed in order to correlate the material composition with the corresponding properties. Among the properties studied we have to mention the water uptake capacity, the rheological properties and the enzyme-mediated degradation behaviour. The results indicate that the HEMA content in the initial polymerization mixtures modulates the architecture of the porous scaffolds from straightforward, top-to-bottom oriented channels for hydrogels possessing the lowest HEMA content to a complex and dense internal porosity of the channels the case of higher HEMA loaded materials. While aiming at tissue engineering applications, it is important to notice that the covalently bound gelatin sequences significantly improve the biocompatibility of PHEMA based hydrogels.".
- aggregation authorList BK788870.
- aggregation endPage "9602".
- aggregation issue "37".
- aggregation startPage "9589".
- aggregation volume "8".
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