Matches in UGent Biblio for { <https://biblio.ugent.be/publication/3118124#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2012".
- aggregation format "application/pdf".
- aggregation hasFormat 3118124.bibtex.
- aggregation hasFormat 3118124.csv.
- aggregation hasFormat 3118124.dc.
- aggregation hasFormat 3118124.didl.
- aggregation hasFormat 3118124.doc.
- aggregation hasFormat 3118124.json.
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- aggregation hasFormat 3118124.txt.
- aggregation hasFormat 3118124.xls.
- aggregation hasFormat 3118124.yaml.
- aggregation isPartOf urn:issn:1932-6203.
- aggregation language "eng".
- aggregation rights "I have retained and own the full copyright for this publication".
- aggregation subject "Veterinary Sciences".
- aggregation title "Effect of recombinant human thyrotropin on the uptake of radioactive iodine (123I) in dogs with thyroid tumors".
- aggregation abstract "In humans, recombinant human thyrotropin (rhTSH) enhances radioactive iodine uptake (RAIU) in patients with differentiated thyroid cancer. No studies have been performed in veterinary medicine to optimize radioiodine treatment of thyroid cancer. The aim of this study was to evaluate the effect of rhTSH on the uptake of radioiodine-123 (I-123) in dogs with thyroid tumors. Nine dogs with thyroid neoplasia were included in this prospective cross-over study. The dogs were divided in 2 groups. In one group, I-123 was administered for a baseline RAIU determination in week 1. In week 2 (after a washout period of 2 weeks), these dogs received rhTSH (100 mu g IV) 24 h before I-123 injection. In the other group the order of the protocol was reversed. For each scan, the dogs received 37 MBq (1 mCi) of I-123 intravenously (IV) and planar scintigraphy was performed after 8 and 24 h for tumor RAIU calculation. Overall, rhTSH administration caused no statistically significant change on thyroid tumor RAIU at 8 h (p = 0.89) or at 24 h (p = 0.98). A significant positive correlation was found between the effect of rhTSH on tumor 8h-RAIU and rhTSH serum concentrations at 6 h (tau = 0.68; p = 0.03), at 12 h (tau = 0.68; p = 0.03) and at 24 h (tau = 0.78; p = 0.02) after rhTSH injection. This study suggests that IV administration of 100 mg rhTSH 24 h before I-123 has an inconsistent effect on thyroid tumor RAIU. Further studies are necessary to determine the best protocol of rhTSH administration to optimize thyroid tumor RAIU.".
- aggregation authorList BK449916.
- aggregation issue "11".
- aggregation volume "7".
- aggregation aggregates 3221639.
- aggregation isDescribedBy 3118124.
- aggregation similarTo journal.pone.0050344.
- aggregation similarTo LU-3118124.