Matches in UGent Biblio for { <https://biblio.ugent.be/publication/3150597#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B442063.
- aggregation creator B442064.
- aggregation creator B442065.
- aggregation creator B442066.
- aggregation creator B442067.
- aggregation creator person.
- aggregation date "2012".
- aggregation format "application/pdf".
- aggregation hasFormat 3150597.bibtex.
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- aggregation hasFormat 3150597.doc.
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- aggregation isPartOf urn:issn:0163-769X.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Imaging of β-cell mass and insulitis in insulin-dependent (type 1) diabetes mellitus".
- aggregation abstract "Insulin-dependent (type 1) diabetes mellitus is a metabolic disease with a complex multifactorial etiology and a poorly understood pathogenesis. Genetic and environmental factors cause an autoimmune reaction against pancreatic beta-cells, called insulitis, confirmed in pancreatic samples obtained at autopsy. The possibility to noninvasively quantify beta-cell mass in vivo would provide important biological insights and facilitate aspects of diagnosis and therapy, including follow-up of islet cell transplantation. Moreover, the availability of a noninvasive tool to quantify the extent and severity of pancreatic insulitis could be useful for understanding the natural history of human insulin-dependent(type 1) diabetes mellitus, to early diagnose children at risk to develop overt diabetes, and to select patients to be treated with immunotherapies aimed at blocking the insulitis and monitoring the efficacy of these therapies. In this review, we outline the imaging techniques currently available for in vivo, noninvasive detection of beta-cell mass and insulitis. These imaging techniques include magnetic resonance imaging, ultrasound, computed tomography, bioluminescence and fluorescence imaging, and the nuclear medicine techniques positron emission tomography and single-photon emission computed tomography. Several approaches and radiopharmaceuticals for imaging beta-cells and lymphocytic insulitis are reviewed in detail.".
- aggregation authorList BK771544.
- aggregation endPage "919".
- aggregation issue "6".
- aggregation startPage "892".
- aggregation volume "33".
- aggregation aggregates 3150627.
- aggregation isDescribedBy 3150597.
- aggregation similarTo er.2011-1041.
- aggregation similarTo LU-3150597.