Matches in UGent Biblio for { <https://biblio.ugent.be/publication/3161328#aggregation> ?p ?o. }
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- aggregation classification "C3".
- aggregation creator person.
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- aggregation date "2012".
- aggregation hasFormat 3161328.bibtex.
- aggregation hasFormat 3161328.csv.
- aggregation hasFormat 3161328.dc.
- aggregation hasFormat 3161328.didl.
- aggregation hasFormat 3161328.doc.
- aggregation hasFormat 3161328.json.
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- aggregation hasFormat 3161328.ris.
- aggregation hasFormat 3161328.txt.
- aggregation hasFormat 3161328.xls.
- aggregation hasFormat 3161328.yaml.
- aggregation language "eng".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Limited versus extended pelvic lymph node dissection in prostate cancer patients".
- aggregation abstract "Introduction & Objectives: Pelvic lymph node dissection (PLND) is currently the most reliable method for staging prostate cancer patients for lymph node metastases. Patients opting for primary external beam radiotherapy undergo a prior staging PLND at our centre based on the risk of lymph node involvement as calculated with Roach’s formula. There is evidence that the increase in lymph nodes removed increases staging accuracy. The aim of this study is to compare the number of lymph nodes removed by limited PLND, removing only the nodes from the obturator fossa, versus extended PLND which comprises removal of at least the nodes from the obturator fossa and along internal and external iliac artery. Complications of both techniques are also compared. Materials & Methods: In this retrospective analysis, 102 patients had a PLND between 2006 and 2011 prior to primary external beam radiotherapy. Postoperative radiographic imaging with CT and MRI performed for radiotherapy planning was used to detect lymphocoeles. We compared limited (n=26) vs. extended (n=76) PLND with regards to retrieval of lymph nodes using student t-test and complications using Fisher’s exact test. Values were expressed as mean (± standard deviation). Except for 4 laparoscopic cases, all limited PLNDs were performed open, and 65 of 76 extended PLNDs were performed laparoscopically. Results: With extended PLND a mean of 16,4 (± 7,8) lymph nodes were removed vs. 9,3 (± 4,3) with limited PLND (p<0.0001). Mean operation time was longer for the extended group (130 (± 38) vs. 89 (± 51) minutes; p=0.007) but mean hospital stay was shorter (4 (± 2,2) vs. 5,8 (± 2,0) days; p=0.0004). Perioperative and postoperative complications were similar for extended vs. limited PLND (5,2% vs. 2,7%; p=1 and 27,6% vs. 34,6%; p=0.66 respectively). Symptomatic lymphocoeles were observed in 7,9% after extended PLND vs. 15,4% after limited PLND (p=0.27), whereas radiographic lymphocoeles were seen in 56,6% vs. 50,0% respectively (p=0.72). Conclusion: In our series laparoscopic extended pelvic lymph node dissection allows for retrieval of almost twice the amount of lymph nodes, thus increasing staging accuracy, with a very limited increase in per- and postoperative complications and radiographic lymphocoeles. It is a safe and effective technique to stage prostate cancer patients for lymph node involvement.".
- aggregation authorList BK250695.
- aggregation isDescribedBy 3161328.
- aggregation similarTo LU-3161328.