Matches in UGent Biblio for { <https://biblio.ugent.be/publication/3206394#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B764570.
- aggregation creator B764571.
- aggregation creator B764572.
- aggregation creator B764573.
- aggregation creator B764574.
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- aggregation date "2013".
- aggregation format "application/pdf".
- aggregation hasFormat 3206394.bibtex.
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- aggregation hasFormat 3206394.doc.
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- aggregation isPartOf urn:issn:0140-7775.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Biology and Life Sciences".
- aggregation title "Luminal uptake of Vibrio (Listonella) anguillarum by shed enterocytes a novel early defence strategy in larval fish".
- aggregation abstract "As adhesion and translocation through fish gut enterocytes of the pathogen Vibrio (Listonella) anguillarum are not well investigated, the effective cause of disease and mortality outbreaks in larval sea bass, Dicentrarchus labrax, suffering from vibriosis is unknown. We detected V.anguillarum within the gut of experimentally infected gnotobiotic sea bass larvae using transmission electron microscopy and immunogold labelling. Intact bacteria were observed in close contact with the apical brush border in the gut lumen. Enterocytes contained lysosomes positive for protein A-gold particles suggesting intracellular elimination of bacterial fragments. Shed intestinal cells were regularly visualized in the gut lumen in late stages of exposure. Some of the luminal cells showed invagination and putative engulfment of bacterial structures by pseudopod-like formations. The engulfed structures were positive for protein A-colloidal gold indicating that these structures were V.anguillarum. Immunogold positive thread-like structures secreted by V.anguillarum suggested the presence of outer membrane vesicles (MVs) hypothesizing that MVs are potent transporters of active virulence factors to sea bass gut cells suggestive for a substantial role in biofilm formation and pathogenesis. We put forward the hypothesis that MVs are important in the pathogenesis of V.anguillarum in sea bass larvae.".
- aggregation authorList BK1133843.
- aggregation endPage "426".
- aggregation issue "4".
- aggregation startPage "419".
- aggregation volume "36".
- aggregation aggregates 3206411.
- aggregation isDescribedBy 3206394.
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