Matches in UGent Biblio for { <https://biblio.ugent.be/publication/390742#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B378060.
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- aggregation date "2007".
- aggregation hasFormat 390742.bibtex.
- aggregation hasFormat 390742.csv.
- aggregation hasFormat 390742.dc.
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- aggregation hasFormat 390742.doc.
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- aggregation isPartOf urn:issn:0105-4538.
- aggregation language "eng".
- aggregation publisher "BLACKWELL PUBLISHING".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Mechanisms of virus-induced asthma exacerbations: state-of-the-art. A GA(2)LEN and InterAirways document".
- aggregation abstract "Viral infections of the respiratory tract are the most common precipitants of acute asthma exacerbations. Exacerbations are only poorly responsive to current asthma therapies and new approaches to therapy are needed. Viruses, most frequently human rhinoviruses (RV), infect the airway epithelium, generate local and systemic immune responses, as well as neural responses, inducing inflammation and airway hyperresponsiveness. Using in vitro and in vivo experimental models the role of various proinflammatory or anti-inflammatory mediators, antiviral responses and molecular pathways that lead from infection to symptoms has been partly unravelled. In particular, mechanisms of susceptibility to viral infection have been identified and the bronchial epithelium appeared to be a key player. Nevertheless, additional understanding of the integration between the diverse elements of the antiviral response, especially in the context of allergic airway inflammation, as well as the interactions between viral infections and other stimuli that affect airway inflammation and responsiveness may lead to novel strategies in treating and/or preventing asthma exacerbations. This review presents the current knowledge and highlights areas in need of further research.".
- aggregation authorList BK682724.
- aggregation endPage "470".
- aggregation issue "5".
- aggregation startPage "457".
- aggregation volume "62".
- aggregation isDescribedBy 390742.
- aggregation similarTo j.1398-9995.2007.01341.x.
- aggregation similarTo LU-390742.