Matches in UGent Biblio for { <https://biblio.ugent.be/publication/4106724#aggregation> ?p ?o. }
Showing items 1 to 54 of
54
with 100 items per page.
- aggregation classification "A1".
- aggregation creator B761126.
- aggregation creator B761127.
- aggregation creator B761128.
- aggregation creator B761129.
- aggregation creator B761130.
- aggregation creator B761131.
- aggregation creator B761132.
- aggregation creator B761133.
- aggregation creator B761134.
- aggregation creator B761135.
- aggregation creator B761136.
- aggregation creator B761137.
- aggregation creator B761138.
- aggregation creator B761139.
- aggregation creator B761140.
- aggregation creator B761141.
- aggregation creator B761142.
- aggregation creator B761143.
- aggregation creator B761144.
- aggregation creator B761145.
- aggregation creator B761146.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2013".
- aggregation format "application/pdf".
- aggregation hasFormat 4106724.bibtex.
- aggregation hasFormat 4106724.csv.
- aggregation hasFormat 4106724.dc.
- aggregation hasFormat 4106724.didl.
- aggregation hasFormat 4106724.doc.
- aggregation hasFormat 4106724.json.
- aggregation hasFormat 4106724.mets.
- aggregation hasFormat 4106724.mods.
- aggregation hasFormat 4106724.rdf.
- aggregation hasFormat 4106724.ris.
- aggregation hasFormat 4106724.txt.
- aggregation hasFormat 4106724.xls.
- aggregation hasFormat 4106724.yaml.
- aggregation isPartOf urn:issn:0002-8703.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Characteristics of children and young adults with Marfan syndrome and aortic root dilation in a randomized trial comparing atenolol and losartan therapy".
- aggregation abstract "Background The Pediatric Heart Network designed a clinical trial to compare aortic root growth and other short-term cardiovascular outcomes in children and young adults with Marfan syndrome randomized to receive atenolol or losartan. We report here the characteristics of the screened population and enrolled subjects. Methods and results Between 2007 and 2011, 21 clinical sites randomized 608 subjects, aged 6 months to 25 years who met the original Ghent criteria and had a body surface area-adjusted aortic root diameter z-score >3.0. The mean age at study entry was 11.2 years, 60% were male, and 25% were older teenagers and young adults. The median aortic root diameter z-score was 4.0. Aortic root diameter z-score did not vary with age. Mitral valve prolapse and mitral regurgitation were more common in females. Among those with a positive family history, 56% had a family member with aortic surgery, and 32% had a family member with a history of aortic dissection. Conclusions Baseline demographic, clinical, and anthropometric characteristics of the randomized cohort are representative of patients in this population with moderate to severe aortic root dilation. The high percentage of young subjects with relatives who have had aortic dissection or surgery illustrates the need for more definitive therapy; we expect that the results of the study and the wealth of systematic data collected will make an important contribution to the management of individuals with Marfan syndrome.".
- aggregation authorList BK1128322.
- aggregation endPage "835".
- aggregation issue "5".
- aggregation startPage "828".
- aggregation volume "165".
- aggregation aggregates 4106772.
- aggregation isDescribedBy 4106724.
- aggregation similarTo j.ahj.2013.02.019.
- aggregation similarTo LU-4106724.