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- aggregation classification "A1".
- aggregation creator B607738.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2013".
- aggregation format "application/pdf".
- aggregation hasFormat 4184111.bibtex.
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- aggregation isPartOf urn:issn:1471-4914.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Biology and Life Sciences".
- aggregation title "Nuclear factor kappa B (NF-κB) in multiple sclerosis pathology".
- aggregation abstract "The nuclear factor kappa B (NF-kappa B) signaling cascade plays a critical role in the regulation of immune and inflammatory responses and has been implicated in the pathogenesis of autoimmune demyelinating diseases such as multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), the main animal model of MS. NF-kappa B is essential for peripheral immune cell activation and the induction of pathology, but also plays crucial roles in resident cells of the central nervous system (CNS) during disease development. Here we review recent evidence clarifying the role of NF-kappa B in the different cell compartments contributing to MS pathology and its implications for the development of therapeutic strategies for the treatment of MS and other demyelinating pathologies of the CNS.".
- aggregation authorList BK965951.
- aggregation endPage "613".
- aggregation issue "10".
- aggregation startPage "604".
- aggregation volume "19".
- aggregation aggregates 4381181.
- aggregation isDescribedBy 4184111.
- aggregation similarTo j.molmed.2013.08.001.
- aggregation similarTo LU-4184111.