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- aggregation classification "A1".
- aggregation creator B677158.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2013".
- aggregation format "application/pdf".
- aggregation hasFormat 4210798.bibtex.
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- aggregation isPartOf urn:issn:0039-2480.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Methods for improved flexural mechanical properties of 3D-plotted PCL-based scaffolds for heart valve tissue engineering".
- aggregation abstract "While porous poly-epsilon-caprolactone (PCL) scaffolds can be manufactured through 3D plotting with high regularity and reproducibility, it has been a challenge in previous research to mimic the highly flexible behaviour of the natural valve leaflets. In this study, an investigation is made of two separate approaches for the improved flexibility of 3D plotted PCL scaffolds for heart valve leaflets. Firstly, the scaffold geometry is radically altered towards a very open woven-like structure by adequately adapting the processing parameters during 3D plotting. Secondly, the base material itself is altered by blending a fraction of low-molecular weight poly-ethylene-oxide (PEO) into the PCL polymer. The scaffolds are 3D plotted for both series and their flexibility is evaluated in a uni-axial indentation experiment. The results are compared to those of the natural valve tissue and it is found that both approaches result in the desired reduction of the stiffness of the scaffold.".
- aggregation authorList BK1040442.
- aggregation endPage "676".
- aggregation issue "11".
- aggregation startPage "669".
- aggregation volume "59".
- aggregation aggregates 4210824.
- aggregation isDescribedBy 4210798.
- aggregation similarTo sv-jme.2013.1003.
- aggregation similarTo LU-4210798.