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- aggregation classification "A1".
- aggregation creator B676586.
- aggregation creator person.
- aggregation date "2013".
- aggregation format "application/pdf".
- aggregation hasFormat 4241361.bibtex.
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- aggregation isPartOf urn:issn:1380-7870.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Mathematics and Statistics".
- aggregation title "On collapsibility and confounding bias in Cox and Aalen regression models".
- aggregation abstract "We study the situation where it is of interest to estimate the effect of an exposure variable on a survival time response in the presence of confounding by measured variables . Quantifying the amount of confounding is complicated by the non-collapsibility or non-linearity of typical effect measures in survival analysis: survival analyses with or without adjustment for typically infer different effect estimands of a different magnitude, even when is not associated with the exposure, and henceforth not a confounder of the association between exposure and survival time. We show that, interestingly, the exposure coefficient indexing the Aalen additive hazards model is not subject to such non-collapsibility, unlike the corresponding coefficient indexing the Cox model, so that simple measures of the amount of confounding bias are obtainable for the Aalen hazards model, but not for the Cox model. We argue that various other desirable properties can be ascribed to the Aalen model as a result of this collapsibility. This work generalizes recent work by Janes et al. (Biostatistics 11:572-582, 2010).".
- aggregation authorList BK1039327.
- aggregation endPage "296".
- aggregation issue "3".
- aggregation startPage "279".
- aggregation volume "19".
- aggregation aggregates 4241424.
- aggregation isDescribedBy 4241361.
- aggregation similarTo s10985-013-9242-z.
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