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- aggregation classification "A1".
- aggregation creator B607062.
- aggregation creator B607063.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2013".
- aggregation format "application/pdf".
- aggregation hasFormat 4266391.bibtex.
- aggregation hasFormat 4266391.csv.
- aggregation hasFormat 4266391.dc.
- aggregation hasFormat 4266391.didl.
- aggregation hasFormat 4266391.doc.
- aggregation hasFormat 4266391.json.
- aggregation hasFormat 4266391.mets.
- aggregation hasFormat 4266391.mods.
- aggregation hasFormat 4266391.rdf.
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- aggregation hasFormat 4266391.txt.
- aggregation hasFormat 4266391.xls.
- aggregation hasFormat 4266391.yaml.
- aggregation isPartOf urn:issn:0960-9822.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Biology and Life Sciences".
- aggregation title "Modeling framework for the establishment of the apical-basal embryonic axis in plants".
- aggregation abstract "The apical-basal axis of the early plant embryo determines the body plan of the adult organism. To establish a polarized embryonic axis, plants evolved a unique mechanism that involves directional, cell-to-cell transport of the growth regulator auxin. Auxin transport relies on PIN auxin transporters [1], whose polar subcellular localization determines the flow directionality. PIN-mediated auxin transport mediates the spatial and temporal activity of the auxin response machinery [2-7] that contributes to embryo patterning processes, including establishment of the apical (shoot) and basal (root) embryo poles [8]. However, little is known of upstream mechanisms guiding the (re)polarization of auxin fluxes during embryogenesis [9]. Here, we developed a model of plant embryogenesis that correctly generates emergent cell polarities and auxin-mediated sequential initiation of apical-basal axis of plant embryo. The model relies on two precisely localized auxin sources and a feedback between auxin and the polar, subcellular PIN transporter localization. Simulations reproduced PIN polarity and auxin distribution, as well as previously unknown polarization events during early embryogenesis. The spectrum of validated model predictions suggests that our model corresponds to a minimal mechanistic framework for initiation and orientation of the apical-basal axis to guide both embryonic and postembryonic plant development.".
- aggregation authorList BK964525.
- aggregation endPage "2518".
- aggregation issue "24".
- aggregation startPage "2513".
- aggregation volume "23".
- aggregation aggregates 4266409.
- aggregation isDescribedBy 4266391.
- aggregation similarTo j.cub.2013.10.038.
- aggregation similarTo LU-4266391.