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- aggregation classification "A1".
- aggregation creator B607161.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2014".
- aggregation format "application/pdf".
- aggregation hasFormat 4270190.bibtex.
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- aggregation isPartOf urn:issn:1526-484X.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Doubling of muscle carnosine concentration does not improve laboratory 1-hr cycling time trial performance".
- aggregation abstract "Muscle carnosine loading through chronic oral beta-alanine supplementation has been shown to be effective for short-duration, high-intensity exercise. This randomised, placebo controlled study explored whether the ergogenic effect of beta-alanine supplementation is also present for longer duration exercise. Subjects (27 well-trained cyclists/triathletes) were supplemented with either beta-alanine or placebo (6.4 g/day) for six weeks. Time to completion and physiological variables for a 1-h cycling time-trial were compared between pre- and post-supplementation. Muscle carnosine concentration was also assessed via proton magnetic resonance spectroscopy before and after supplementation. Following beta-alanine supplementation, muscle carnosine concentration was increased by 143 ± 151% (mean ± SD; p < 0.001) in the gastrocnemius and 161 ± 56% (p < 0.001) in the soleus. Post-supplementation time trial performance was significantly slower in the placebo group (60.6 ± 4.4 to 63.0 ± 5.4 min; p < 0.01) and trended towards a slower performance following beta-alanine supplementation (59.8 ± 2.8 to 61.7 ± 3.0 min; p = 0.069). We found an increase in lactate/proton concentration ratio following beta-alanine supplementation during the time-trial (209.0 ± 44.0 (beta-alanine) vs. 161.9 ± 54.4 (placebo); p < 0.05), indicating that a similar lactate concentration was accompanied by a lower degree of systemic acidosis, even though this acidosis was quite moderate (pH ranging from 7.30-7.40). In conclusion, chronic beta-alanine supplementation in well-trained cyclists had a very pronounced effect on muscle carnosine concentration and a moderate attenuating effect on the acidosis associated with lactate accumulation, yet without affecting 1-h time-trial performance under laboratory conditions.".
- aggregation authorList BK964718.
- aggregation endPage "324".
- aggregation issue "3".
- aggregation startPage "315".
- aggregation volume "24".
- aggregation aggregates 4270206.
- aggregation aggregates 5335404.
- aggregation isDescribedBy 4270190.
- aggregation similarTo ijsnem.2013-0125.
- aggregation similarTo LU-4270190.