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- aggregation classification "B2".
- aggregation creator B1011584.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2013".
- aggregation format "application/pdf".
- aggregation hasFormat 4362087.bibtex.
- aggregation hasFormat 4362087.csv.
- aggregation hasFormat 4362087.dc.
- aggregation hasFormat 4362087.didl.
- aggregation hasFormat 4362087.doc.
- aggregation hasFormat 4362087.json.
- aggregation hasFormat 4362087.mets.
- aggregation hasFormat 4362087.mods.
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- aggregation hasFormat 4362087.txt.
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- aggregation hasFormat 4362087.yaml.
- aggregation isPartOf urn:isbn:9781627034951.
- aggregation isPartOf urn:isbn:9781627034968.
- aggregation isPartOf urn:issn:1064-3745.
- aggregation language "eng".
- aggregation publisher "Humana Press".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Biology and Life Sciences".
- aggregation title "PAMPs and DAMPs in allergy exacerbation models".
- aggregation abstract "Sensitization of mice to real-life allergens or harmless antigen with the use of adjuvants will lead to the induction of DAMPs in the immune system. We have shown that the Th2-inducing adjuvant aluminum hydroxide or exposure of the airways to house dust mite leads to the release of DAMPs: uric acid, ATP, and IL-1. Exposure to DAMPs or PAMPs present in allergens or added to harmless allergens, such as the experimental allergen ovalbumin, induces several immune responses, including cellular influx and activation. Cellular influx can be analyzed by flow cytometry. Likewise, cellular activation can be assessed by measuring increased expression and release of chemokines and cytokines. These inflammatory mediators can be analyzed by ELISA or confocal microscopy. Here, we describe the protocols for these assessments and a protocol that takes advantage of bone marrow chimeric mice to further elucidate mechanism.".
- aggregation authorList BK1418846.
- aggregation endPage "204".
- aggregation startPage "185".
- aggregation volume "1032".
- aggregation aggregates 4362097.
- aggregation isDescribedBy 4362087.
- aggregation similarTo 978-1-62703-496-8_15.
- aggregation similarTo LU-4362087.