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- aggregation classification "B2".
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2013".
- aggregation format "application/pdf".
- aggregation hasFormat 4364794.bibtex.
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- aggregation isPartOf urn:isbn:9781627030281.
- aggregation isPartOf urn:isbn:9781627030298.
- aggregation isPartOf urn:issn:1064-3745.
- aggregation language "eng".
- aggregation publisher "Humana Press".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "CE analysis of γ-globulin mobility and potential clinical utility".
- aggregation abstract "Serum protein electrophoresis is widely used in clinical laboratories to measure the relative abundance of each obtained fraction. Moreover, we found that the migration time of the g-globulin fraction can be reproducibly determined (CV = 1.1%). Immunoglobulins were purified from serum using protein l-agarose and their N-glycosylation was studied using CE on a DNA sequencer. Liver fibrosis patients showed a lower level of sialylation and this moderately correlates with the migration time of the g-globulins (r = 0.2– 0.4). This allowed us to differentiate healthy individuals from these patients with an acceptable diagnostic accuracy (area under the curve = 0.75). This glycomics approach could become a significant added value to a daily, routine clinical test.".
- aggregation authorList BK1449344.
- aggregation endPage "257".
- aggregation startPage "249".
- aggregation volume "919".
- aggregation aggregates 4364795.
- aggregation isDescribedBy 4364794.
- aggregation similarTo 978-1-62703-029-8_22.
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